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MetabolomicsEffects of coronatine elicitation on growth and metabolic profiles of Lemna paucicostata culture
In this study, the effects of coronatine treatment on the growth, comprehensive metabolic profiles, and productivity of bioactive compounds, including phenolics and phytosterols, in whole plant cultures of Lemna paucicostata were investigated using gas chromatography-mass spectrometry (GC-MS) couple...
2018-09-11 | MTBLS526 | MetaboLights
TranscriptomicsGeneration of Integration-free Induced Neural Stem Cells from Mouse Fibroblasts
Recent studies demonstrated that fibroblasts could be converted into induced neural stem cells (iNSCs). However, the insertional mutation caused by random integration of viral vectors has been a major limitation of iNSCs for the future clinical translation. Here we show that non-viral transfection o...
ORGANISM(S): Mus musculus 
2015-03-27 | E-GEOD-67319 | biostudies-arrayexpress
MetabolomicsPFKFB3-mediated glycolysis boosts fibroblast activation and subsequent kidney fibrosis

Renal fibrosis, a hallmark of chronic kidney diseases, is driven by the activation of renal fibroblasts. Recent studies have highlighted the role of glycolysis in this process. Nevertheless, one critical glycolytic activator, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3), remain...

2024-03-12 | MTBLS8281 | MetaboLights
TranscriptomicsGeneration of parthenogenetic iPS cells from parthenogenetic neural stem cell
In pluripotential reprogramming, a pluripotent state is established within somatic cells. In this study, we have generated induced pluripotent stem (iPS) cells from bi-maternal (uniparental) parthenogenetic neural stem cells (pNSCs) by transduction with four (Oct4, Klf4, Sox2, and c-Myc) or two (Oct...
ORGANISM(S): Mus musculus 
2010-05-20 | E-GEOD-15561 | biostudies-arrayexpress
UnknownAn integrated encyclopedia of DNA elements in the human genome.
Not available
S-EPMC3439153 | biostudies-literature
UnknownOral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes: A Secondary Analysis of the SOUL Randomized Clinical Trial.
Not available
S-EPMC12865694 | biostudies-literature
UnknownImpact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial.
Not available
S-EPMC12824789 | biostudies-literature
UnknownNew genetic loci link adipose and insulin biology to body fat distribution.
Not available
S-EPMC4338562 | biostudies-literature
UnknownFactors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial.
Not available
S-EPMC11187765 | biostudies-literature
UnknownGenetic studies of body mass index yield new insights for obesity biology.
Not available
S-EPMC4382211 | biostudies-literature
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