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Several studies have reported an association between phthalate exposure and an increased risk of atopic dermatitis (AD). However, the molecular mechanism underlying this phenomenon in children remains unknown. In this study, we investigated the effect of Dibutyl Phthalate (DBP), one of the phthalate...
ORGANISM(S): Homo sapiens (Human) 
2026-06-20 | PXD053710 | Pride
To efficiently identify genetic susceptibility variants for gastric cancer, including rare coding variants, we performed an exome chip-based array study. We found that a linkage disequilibrium (LD) block containing 2 significant variants in PSCA gene increased the risk and two blocks that included 1...
ORGANISM(S): Homo sapiens 
Since the first generation of induced Pluripotent Stem cells (iPSCs), several reprogramming systems have been used to study its molecular mechanisms. However, the system of choice largely affects the reprogramming efficiency, influencing our view on the mechanisms. Here we demonstrate that reprogram...
ORGANISM(S): Mus musculus 
Proteome dynamics of mouse embryonic fibroblast reprograming into iPS cells
ORGANISM(S): Mus Musculus 
2014-12-31 | PAe005212 | PeptideAtlas
Vascular calcification (VC) is often associated with cardiovascular and metabolic diseases. However, the molecular mechanisms linking VC to these diseases have yet to be elucidated. Here we report that MDM2-induced polyubiquitination of histone deacetylase 1 (HDAC1) mediates VC. Loss of HDAC1 activi...
ORGANISM(S): Rattus norvegicus 
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