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Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo sapiens (Human) 
2016-07-06 | PXD001237 | Pride
This SuperSeries is composed of the following subset Series:; GSE9130: aP2-nSREBP1c_white_Adipose_Tissue_expression_differentials; GSE9131: Pparg_white_Adipose_Tissue_expression_differentials Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
Identifying gene expression changes in adipose tissue of lipodystrophic Pparg targeted mice Experiment Overall Design: RNA from epididymal white adipose pads of three 10-week-old Pparg males and three litter-matched WT controls was analyzed by MOE430v2.0 GeneChipâ?¢ arrays, one mouse p...
ORGANISM(S): Mus musculus 
Identifying gene expression changes in adipose tissue of lipodystrophic aP2-nSREBP1c trangenic mice Experiment Overall Design: RNA from epididymal white adipose pads of three 10-week-old aP2-nSREBP1c transgenic males and three litter-matched WT controls was analyzed by MOE430v2.0 GeneChipâ„¢ arrays,...
ORGANISM(S): Mus musculus 
Recently it was shown that gene expression signatures generated from DNA microarray analyses have promise as biomarkers of clinical outcome and that the molecular characteristics of tumors could be elucidated. Through this study, we have determined a high-risk signature for recurrence as a prognosti...
ORGANISM(S): Homo sapiens 
Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080728 | MassIVE
Lung disease causes most of the morbidity and mortality in cystic fibrosis (CF). However, understanding its pathogenesis has been hindered by lack of an animal model with characteristic features of CF. To overcome this problem, we recently generated pigs with targeted CFTR genes. We now report that ...
ORGANISM(S): Sus scrofa 
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