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TranscriptomicsToxoplasma gondii arginine methyltransferase 1 (PRMT1) regulates parasite counting during tachyzoite cell division
PRMT1 is thought to be responsible for the majority of PRMT activity in Toxoplasma gondii, but its exact function is unknown. We generated T. gondii mutants lacking PRMT1 (∆prmt1) by deletion of the PRMT1 gene. ∆prmt1 parasites exhibit morphological defects during cell division and grow slowly, and ...
ORGANISM(S): Toxoplasma gondii 
2015-09-18 | E-GEOD-73177 | biostudies-arrayexpress
TranscriptomicsHigh Mobility Group protein HMGB2 is a Critical Regulator of Plasmodium Oocyst Development
Two mice per group were infected with one million purified schizonts from the WT and two clones (B3 and D1) of the pyhmgb2 KO lines. Parasitemia reached 10 to 20 % and equivalent gametocytemia total RNA was extracted from the WT and the B3 and D1 clones of the KO parasite lines using the Trizol meth...
ORGANISM(S): Plasmodium yoelii 
2008-04-19 | E-GEOD-9952 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of salt fractions maps physical properties of chromatin
We applied genome-wide profiling to successive salt-extracted fractions of micrococcal nuclease-treated Drosophila chromatin. Chromatin fractions extracted with 80mM or 150mM NaCl after digestion contain predominantly mononucleosomes and represent calssical 'active' chromatin. Profiles of these low-...
ORGANISM(S): Drosophila melanogaster 
2008-12-11 | E-GEOD-13217 | biostudies-arrayexpress
UnknownSHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Not available
S-EPMC4533874 | biostudies-literature
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