Sort   by:  
 Page size 
TranscriptomicsMicroRNAs are required for the feature maintenance and differentiation of brown adipocytes
Brown adipose tissue is specialized to burn lipids for heat generation as a natural defense against cold and obesity. Previous studies established microRNAs as essential regulators of brown adipocyte differentiation, but it remains unknown whether microRNAs are required for the feature maintenance o...
ORGANISM(S): Mus musculus 
2014-08-07 | E-GEOD-60165 | biostudies-arrayexpress
GenomicsGenome-wide analysis of histone modifications in latently HIV-1 infected T cells
The epigenetic mechanisms established by histone modifications may affect the transcriptional silencing of HIV-1 and viral latency. A systematic epigenome profiling could be applicable to develop new epigenetic diagnostic markers for detecting HIV-1 latency. In this study, histone modification prof...
ORGANISM(S): Homo sapiens 
2014-06-06 | E-GEOD-58247 | biostudies-arrayexpress
UnknownSETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway.
Not available
S-EPMC4333197 | biostudies-literature
TranscriptomicsAnti-tumor activity and acquired resistance mechanism of Dovitinib (TKI258) in RET rearranged lung adenocarcinoma
RET rearrangement is a newly identified oncogenic mutation in lung adenocarcinoma (LADC). Activity of dovitinib (TKI258), a potent inhibitor of FGFR, VEGFR, and PDGFR, in RET-rearranged LADC has not been reported. The aims of the study are to explore anti-tumor effects and mechanisms of acquired res...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-69226 | biostudies-arrayexpress
TranscriptomicsRegulation of Angiogenesis by EZH2
While VEGF-targeted therapies are showing promise in clinical studies, new angiogenesis targets are needed to make additional gains. Here, we show that increased Zeste homologue 2 (EZH2) expression in either tumor cells or in tumor vasculature is predictive of poor clinical outcome. The increase in ...
ORGANISM(S): Homo sapiens 
2010-10-12 | E-GEOD-20381 | biostudies-arrayexpress
UnknownManagement of severe sepsis in patients admitted to Asian intensive care units: prospective cohort study.
Not available
S-EPMC3113333 | biostudies-literature
UnknownEarlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis.
Not available
S-EPMC4879711 | biostudies-literature
UnknownRandomized clinical trial evaluating intravitreal ranibizumab or saline for vitreous hemorrhage from proliferative diabetic retinopathy.
Not available
S-EPMC4217122 | biostudies-literature
UnknownComprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.
Not available
S-EPMC4864952 | biostudies-literature
UnknownRepeated intravitreous ranibizumab injections for diabetic macular edema and the risk of sustained elevation of intraocular pressure or the need for ocular hypotensive treatment.
Not available
S-EPMC4496789 | biostudies-literature
Sort   by:  
 Page size