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GenomicsPharmacological and genomic profiling identifies NFκB-targeted treatment strategies for mantle cell lymphoma
Mantle cell lymphoma (MCL) is an aggressive malignancy characterized by poor prognosis, underscoring the need for novel therapeutic strategies1. In this study, we employed large-scale pharmacological profiling of 16 pathway inhibitors across more than 100 hematological cell line models to identify n...
EGAS00001000622 | EGA
Genomicsena-DATASET-BCCA-06-12-2013-17:57:13:627-21 - samples
Complete set of bam files associated with study EGAS00001000622
EGAD00001000702 | EGA
Proteomics,MultiomicsCyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080728 | MassIVE
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