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TranscriptomicsTranscription profiling of mouse CD4 cells isolated from an ENU induced mutant Sanroque vs. wildtype
Male C57BL/6 mice were treated with ENU to generate single base substitutions, the variant genome sequences were breed to homozygosity in inbreeding pedigrees, and screened for antinuclear autoantibodies (ANA). The sanroque pedigree contained multiple progeny with ANA of mixed homogeneous nuclear a...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2376 | biostudies-arrayexpress
UnknownIdentification of novel bioactive molecules from garlic bulbs: A special effort to determine the anticancer potential against lung cancer with targeted drugs.
Not available
S-EPMC7715046 | biostudies-literature
UnknownTreatment Outcomes and Safety of Mobocertinib in Platinum-Pretreated Patients With EGFR Exon 20 Insertion-Positive Metastatic Non-Small Cell Lung Cancer: A Phase 1/2 Open-label Nonrandomized Clinical Trial.
Not available
S-EPMC8517885 | biostudies-literature
TranscriptomicsIdentification of transcripts whose abundance changes in response to acute switches in DSX isoform in the ovary and testis
RNAseq of dissected adult ovary and testis after DSX isoform is switched using temperature inducible alleles or constructs. Biological duplicates were sequenced for each genotype at each condition.
ORGANISM(S): Drosophila melanogaster 
2016-03-17 | E-GEOD-79294 | biostudies-arrayexpress
TranscriptomicsIdentification of transcripts whose abundance changes in response to acute switches in DSX isoform
RNAseq of dissected adult fat body after DSX isoform is switched using temperature inducible alleles or constructs. Biological duplicates were sequenced for each genotype at each condition.
ORGANISM(S): Drosophila melanogaster 
2014-10-30 | E-GEOD-55848 | biostudies-arrayexpress
UnknownArabidopsis HEAT SHOCK FACTOR BINDING PROTEIN is required to limit meiotic crossovers and HEI10 transcription
Not available
S-SCDT-10_15252-EMBJ_2021109958 | biostudies-other
TranscriptomicsTranscriptome analysis of rice (Oryza sativa cv.TW16) in relation to infection with rice tungro spherical virus (RTSV)
Rice tungro disease is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. Infection with RTSV alone does not result in any distinctive symptoms in TW16 that is one of RTSV resistant indica rice. To elucidate the basis of asymptomatic response of r...
ORGANISM(S): Oryza sativa Indica Group 
2010-05-18 | E-GEOD-16140 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of rice (Oryza sativa cv. Taichung Native 1) in relation to infection with RTSV
Rice tungro disease is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. Infection with RTSV alone does not result in any distinctive symptoms in Taichung Native 1 (TN1) that is one of RTSV susceptive indica rice cultivar. To elucidate the basis ...
ORGANISM(S): Oryza sativa Indica Group 
2010-05-18 | E-GEOD-16141 | biostudies-arrayexpress
GenomicsIdentifying targets of DSX with DamID-seq
We have adapted the DamID protocol for use with high throughput sequencing. We have used DamID to identify the positions within the Drosophila genome where the transcription factor DSX is bound. We sequenced DpnI-digested genomic DNA from fly tissues containing UAS-Dam (control) or UAS-Dam-DsxF or ...
ORGANISM(S): Drosophila melanogaster 
2014-10-30 | E-GEOD-27269 | biostudies-arrayexpress
TranscriptomicsPrediction of gene activity based on an integrated multi-omics approach.
An increasingly common method for predicting gene activity is genome-wide chromatin immunoprecipitation of M-bM-^@M-^XactiveM-bM-^@M-^Y chromatin modifications followed by massively parallel sequencing (ChIP-seq). Using a novel ChIP-seq quantification method (cRPKM), we tested the power of such ChIP...
ORGANISM(S): Mus musculus 
2013-11-19 | E-GEOD-52450 | biostudies-arrayexpress
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