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TranscriptomicsIdentification of novel mechanosensitive genes differentially regulated at 48 h timepoint in vivo using mouse carotid artery endothelium exposed to disturbed blood flow
Recently, we showed that disturbed flow caused by a partial ligation ofmouse carotid artery rapidly induces atherosclerosis. Analysis of mechanosenstive microRNA in the mouse carotid endothelium. In this study, we examined the microRNAs that respond differentially to blood flow pattern in the mouse ...
ORGANISM(S): Mus musculus 
2014-01-13 | E-GEOD-52243 | biostudies-arrayexpress
TranscriptomicsNumber of vertebrae is fine-tuned by Notch signaling via control of period of the somite segmentation clock.
The number of vertebrae is strictly defined for any given species1, and depends on the number of somites, which are periodically formed as perfectly matched cell masses during mid-embryogenesis, where the somite segmentation clock prescribes the timing2. The tempo of the clock is affected by surroun...
ORGANISM(S): Mus musculus 
2010-10-01 | E-GEOD-18419 | biostudies-arrayexpress
UnknownSynthesis of heteroleptic [Sr(ddemap)(tmhd)]<sub>2</sub> and its use in atomic layer deposition of low carbon SrO thin films.
Not available
S-EPMC12822820 | biostudies-literature
TranscriptomicsMus musculus hematopoietic stem cell
A transcriptome study in mouse hematopoietic stem cells was performed using a sensitive SAGE method, in an attempt to detect medium and low abundant transcripts expressed in these cells. Among a total of 31,380 unique transcript, 17,326 (55%) known genes were detected, 14,054 (45%) low-copy transcri...
ORGANISM(S): Mus musculus 
2009-05-20 | E-GEOD-16139 | biostudies-arrayexpress
UnknownThe atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis.
Not available
S-EPMC3923891 | biostudies-literature
TranscriptomicsC2C12 murine myoblast cell line and 48 h 10 uM BIO treated C2C12 cellulate
In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BIO) to attempt to reproduce this behavior in mammalian muscle culture. C2C12 myotubes derived from th...
ORGANISM(S): Mus musculus 
2011-12-08 | E-GEOD-34238 | biostudies-arrayexpress
TranscriptomicsFrizzled 4 regulates stemness and invasiveness of migrating glioma cells established by serial in vivo intracranial transplantation
One of the most detrimental hallmarks of glioblastoma multiforme (GBM) is cellular invasiveness, considered a potential cause of tumor recurrence. Infiltrated GBM cells are difficult to completely eradicate surgically and with local therapeutic modalities. Although much effort has focused on unders...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21570 | biostudies-arrayexpress
OtherA draft map of rhesus monkey tissue proteome for biomedical research.
Data from ProteomeXchange, PXD ID: PXD001972. Experiment: male, file: MALE_PROSTATE_MID.msf.mgf. Published as part of PLoS One. 2015 May 14;10(5):e0126243 . From the Abstract: {{i}} Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases becau...
ORGANISM(S): Homo_sapiens_viruses, Rhesus_monkey_papillomavirus_1_uid14025, Rhesus 
GPM32310019946 | GPMDB
Resource Reanalysis 
TranscriptomicsSingle-cell transcriptome profiling for metastatic renal cell carcinoma patient-derived cells [aCGH]
Clear cell renal cell carcinoma (ccRCC) initiated from the renal epithelium is the most prevalent histological type of adult kidney cancers. Dissecting intratumoral heterogeneity (ITH) of ccRCC has leveraged to extend our knowledge on how primary tumors harboring driver mutations evolve and spread t...
ORGANISM(S): Homo sapiens 
2015-09-18 | E-GEOD-73119 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptome profiling for metastatic renal cell carcinoma patient-derived cells [RNA-seq]
Clear cell renal cell carcinoma (ccRCC) initiated from the renal epithelium is the most prevalent histological type of adult kidney cancers. Dissecting intratumoral heterogeneity (ITH) of ccRCC has leveraged to extend our knowledge on how primary tumors harboring driver mutations evolve and spread t...
ORGANISM(S): Homo sapiens 
2015-09-18 | E-GEOD-73121 | biostudies-arrayexpress
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