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ProteomicsAn integrative multi-omics approach to characterize prebiotic inulin effects on Faecalibacterium prausnitzii
Faecalibacterium prausnitzii, a major commensal bacterium in the human gut, is well known for its anti-inflammatory effects, which improve host intestinal health. Although several studies have reported that inulin, a well-known prebiotic, increases the abundance of F. prausnitzii in the intestine, t...
ORGANISM(S): Faecalibacterium prausnitzii A2-165 Bacteria 
2022-04-04 | PXD030078 | Pride
Prebiotics Pts transporter Beta-fructosidase Abc transporter Faecalibacterium prausnitzii Amylosucrase Inulin Lc-ms/ms 
ProteomicsUnveiling the inhibition mechanism of Clostridioides difficile by Bifidobacterium longum via multiomics approach
A major risk factor for Clostridioides difficile infection (CDI) is the perturbation of the gut microbiota by antibiotic administration, and antibiotic therapy, the standard treatment option for CDI, exacerbates the imbalance of the gut microbiota, leading to a very high recurrent CDI (rCDI) inciden...
ORGANISM(S): Clostridioides difficile ATCC 9689 = DSM 1296 
2024-01-26 | PXD040738 | Pride
Metabolomics Microbe-microbe interaction Clostridioides difficile Molecular mechanism. Bifidobacterium longum Proteomics 
TranscriptomicsPatient specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ (gene expression)
Frequent discrepancies between preclinical and clinical results of anti-cancer agents demand a reliable translational platform that can precisely recapitulate the biology of human cancers. Another critical unmet need is the ability to predict therapeutic responses for individual patients. Toward thi...
ORGANISM(S): Homo sapiens 
2013-01-18 | E-GEOD-42669 | biostudies-arrayexpress
TranscriptomicsPatient specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ (CGH)
Frequent discrepancies between preclinical and clinical results of anti-cancer agents demand a reliable translational platform that can precisely recapitulate the biology of human cancers. Another critical unmet need is the ability to predict therapeutic responses for individual patients. Toward thi...
ORGANISM(S): Homo sapiens 
2013-01-18 | E-GEOD-42577 | biostudies-arrayexpress
UnknownPhloroglucinol Attenuates the Cognitive Deficits of the 5XFAD Mouse Model of Alzheimer's Disease.
Not available
S-EPMC4540482 | biostudies-literature
UnknownLong-term outcome of Bartter syndrome in 54 patients: A multicenter study in Korea.
Not available
S-EPMC10040751 | biostudies-literature
UnknownExtracellular Vesicle Proteome Analysis Improves Diagnosis of Recurrence in Triple-Negative Breast Cancer.
Not available
S-EPMC12183389 | biostudies-literature
UnknownLong-Term (7-Year) Clinical Implications of Newly Unveiled Asymptomatic Abnormal Ankle-Brachial Index in Patients With Coronary Artery Disease.
Not available
S-EPMC8751871 | biostudies-literature
UnknownStructural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.
Not available
S-EPMC419904 | biostudies-literature
UnknownTime-Dependent Impact of Sex on the Long-Term Outcomes After Left Main Revascularization.
Not available
S-EPMC9075067 | biostudies-literature
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