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Undheim EAB, Jones A, Clauser KR, Holland JW, Pineda SS, King GF, Fry BG. Mol Biol Evol, 2014 31: p?-?.
ORGANISM(S): Thereuopoda Longicornis(centipede) Scolopendra Morsitans(centipede) Cormocephalus Westwoodi(centipede) Ethmostigmus Rubripes(centipede) 
2014-04-02 | MSV000078573 | MassIVE
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
Missense FBXW7 mutations are prevalent in various tumors, including T-cell acute lymphoblastic leukemia (T-ALL). To study the effects of such lesions, we generated animals carrying regulatable Fbxw7 mutant alleles. We show here that these mutations specifically bolster cancer-initiating cell activit...
ORGANISM(S): Mus musculus 
We identified the ubiquitin ligase Huwe1 as a crucial regulator of hematopoietic stem cell (HSC) functions. We generated Huwe1 conditional knock-out mice and discovered that the loss of this ligase causes an increased proliferation and stem cell exhaustion, together with a decreased lymphoid specifi...
ORGANISM(S): Mus musculus 
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