Cell competition, the context-dependent cell elimination via short-range cell-cell interactions, was originally described in Drosophila, where heterozygous ribosomal protein (Rp+/-) mutant cells are outcompeted by wild-type neighbors. The transcription factor Xrp1 mediates most Rp+/- phenotypes, inc...
ORGANISM(S): Drosophila melanogaster (Fruit fly)