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TranscriptomicsComprehensive analysis of microRNA expression in the human developing brain reveals microRNA-10 as a caudalizing factor
MicroRNAs (miRNAs) have been implicated in regulating multiple processes during brain development in various species. However, the function of miRNAs in human brain development remains largely unexplored. Here, we provide a comprehensive analysis of miRNA expression of regionalized neural progenitor...
ORGANISM(S): Homo sapiens 
2015-04-23 | E-GEOD-68189 | biostudies-arrayexpress
TranscriptomicsComprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factorl
MicroRNAs (miRNAs) have been implicated in regulating multiple processes during brain development in various species. However, the function of miRNAs in human brain development remains largely unexplored. Here, we provide a comprehensive analysis of miRNA expression of regionalized neural progenitor...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-71204 | biostudies-arrayexpress
GenomicsModelling rostro-caudal neural tube regionalization from human embryonic stem cells with a microfluidic morphogenic gradient
Modelling rostro-caudal neural tube regionalization from human embryonic stem cells with a microfluidic morphogenic gradient
PRJNA558753 | ENA
ProteomicsIdentifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells
Ventral midbrain (VM) dopaminergic progenitor cells derived from human pluripotent stem cells have the potential to replace endogenously lost dopamine neurons and are currently in preclinical and clinical development for treatment of Parkinson’s Disease (PD). However, one main challenge in the quali...
ORGANISM(S): Homo sapiens (Human) 
2023-12-13 | PXD039510 | Pride
Parkinson’s disease Cell replacement therapy Mass spectrometry Dopaminergic progenitors Biomarkers 
TranscriptomicsSingle-cell RNA sequencing of developing human neural organoids exposed to an array of morphogen treatments varying morphogen concentration, timing and combinatorics
This experiment seeks to unravel the effects of concentration, timing and combinatorial variables on the response to morphogens during early human neural organoid development. Human neural organoids derived from three different hESC lines were cultured individually and exposed to systematic variatio...
ORGANISM(S): Homo sapiens 
2025-10-15 | E-MTAB-15667 | biostudies-arrayexpress
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