Sort   by:  
 Page size 
UnknownPhase II Study of Gemcitabine, Carboplatin, and Iniparib As Neoadjuvant Therapy for Triple-Negative and BRCA1/2 Mutation-Associated Breast Cancer With Assessment of a Tumor-Based Measure of Genomic Instability: PrECOG 0105.
Not available
S-EPMC4451172 | biostudies-literature
UnknownTBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer.
Not available
S-EPMC4451173 | biostudies-literature
TranscriptomicsArrays of time course experiment (2-28 d) laser microdissected samples of H. pylori -infected mice
Mice were infected with Helicobacter pylori strain SS1 for 2, 7, 14 or 28 days or left uninfected. They were sacrificed at the appropriate times, the stomachs were removed and one half was plated for colony counts. The other half was embedded in OCT and cryosections were produced for 6-7 animals per...
ORGANISM(S): Mus musculus 
2012-05-11 | E-GEOD-37938 | biostudies-arrayexpress
TranscriptomicsLuminal-like and basal-like in vivo breast cancer xenograft models
The number of relevant and well-characterized cell lines and xenograft models for studying human breast cancer are few, and may represent a limitation for this field of research. With the aim of developing new breast cancer model systems for in vivo studies of hormone dependent and independent tumor...
ORGANISM(S): Homo sapiens 
2010-07-22 | E-GEOD-23041 | biostudies-arrayexpress
TranscriptomicsExpression data from cell lines originating from patients with multiple myeloma, plasmacytoma and diffuse large B-cell lymphoma
A predictive gene list for response to high dose melphalan therapy in patients diagnosed with multiple myeloma is generated by combining results from dose response experiments and microarray data using a B-cell line panel and the introduction of multivariate regression techniques. 18 malignant B-cel...
ORGANISM(S): Homo sapiens 
2011-04-30 | E-GEOD-22759 | biostudies-arrayexpress
TranscriptomicsATF3 is a positive regulator of human IFN gene expression
The aim of this study was to identify genes regulated by IL-12, IL-18 and IFN-alpha during early differentiation of human Th1 cells Human cord blood CD4+ T cells were activated via TCR and cultured in the presence of IL-12, IFN-alpha or IL-12+IL-18. Cytokine induced gene expression was compared to a...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-20198 | biostudies-arrayexpress
TranscriptomicsExpression data from Transgenic mice skin expressing deltaNp63alpha
We developed a Tet-inducible system to express deltaNp63alpha isoform under the control of keratin 5 promoter. Transgenic mice, which were Bigenic (BG) developed a severe skin phenotype with abnormal keratinocyte differentiation and defects in hair follicle development and cycling. Skin samples from...
ORGANISM(S): Mus musculus 
2010-04-28 | E-GEOD-20514 | biostudies-arrayexpress
TranscriptomicsExpression data from SSEA1+ c-kit+ differentiated murine embryonic stem cells
SSEA1+ c-kit+cells sorted from mouse embryonic stem cells differentiated for 4 days in 10uM Retinoic acid do not form teratomas when transplated into SCID mice while Pten-/- cells do. We used microarrays to identify genes and pathways besides Pten that could explain this difference in tumorigenicity...
ORGANISM(S): Mus musculus 
2010-11-19 | E-GEOD-25465 | biostudies-arrayexpress
TranscriptomicsThe Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels
Astrocytes, the most prominent glial cell type in the brain, send specialized processes called endfeet around blood vessels and express a large molecular repertoire regulating the cerebrovascular system physiology. One of the most striking properties of astrocyte endfeet is their enrichment in gap j...
ORGANISM(S): Mus musculus 
2015-03-03 | E-GEOD-59148 | biostudies-arrayexpress
GenomicsAllele-specific binding of ZFP57 in the regulation of imprinted and mono-allelic expression
Selective maintenance of genomic methylation imprints during pre-implantation development is required for parental origin-specific expression of imprinted genes. The Kruppel-like zinc finger protein ZFP57 acts as a factor necessary for maintaining the DNA methylation memory at multiple imprinting co...
ORGANISM(S): Mus musculus 
2015-05-08 | E-GEOD-55382 | biostudies-arrayexpress
Sort   by:  
 Page size