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TranscriptomicsAFP1 kO: Expression profiling analysis of embryonic and adult liver
The alpha-fetoprotein (AFP) gene is a member of the albumin gene family and encodes a serum glycoprotein with an onco-fetal pattern of expression. AFP is produced in high concentrations during embryonic life by the hepatocytes and the visceral endoderm of the yolk sac and to a lesser extent by the d...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-20561 | biostudies-arrayexpress
TranscriptomicsExpression profiling analysis of lung, heart and bone of AGA002 mutant mice
Col1a1 is located on mouse distal chromosome 11 (Celera 94607393-94622990bp; 15kb) and encodes type I procollagen that associates stoichiometrically with col1a2 in forming secreted type I mature collagen that self-assembles into a supramolecular fibrillar structure consisting of a protein family. Ty...
ORGANISM(S): Mus musculus 
2010-06-01 | E-GEOD-12847 | biostudies-arrayexpress
MetabolomicsGNPS - The nutritional and host environment shapes community ecology and keystone functions in a synthetic gut bacterial community
Microbe-microbe interactions are critical for gut microbiome function. A challenging task to understand health and disease-related microbiome signatures is to move beyond descriptive community-level profiling towards disentangling microbial interaction networks. Here, we aimed to determine members t...
ORGANISM(S): Bacteria (ncbitaxon:2) Mus Sp. (ncbitaxon:10095) 
2022-11-14 | MSV000090704 | GNPS
TranscriptomicsTranscription profiling of glucocorticoid resistant and sensitive acute lymphoblastic leukemia cell lines
Gene expression data of glucocorticoid resistant and sensitive acute lymphoblastic leukemia cell lines for the article: Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells Glucocortic...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-22152 | biostudies-arrayexpress
TranscriptomicsExpression Data From Dietary Restriction, p53 Knockdown and sir2 Overexpression Mutants
Expression data from four different lifespan-extending conditions: dietary restriction in two different genetic backgrounds (canton-s and a yw, w1118 combination), sir2 overexpression and p53 knockdown (+/-). Comparison of significantly over and under-expressed genes reveals a signature for dietary ...
ORGANISM(S): Drosophila melanogaster 
2011-01-20 | E-GEOD-26726 | biostudies-arrayexpress
TranscriptomicsCrosstalk between two bZIP signaling pathways orchestrates salt-induced metabolic reprogramming in Arabidopsis roots
Soil salinity increasingly causes crop losses worldwide. Although roots are the primary targets of salt stress, the signaling networks that facilitate metabolic reprogramming to induce stress tolerance are less understood than those in leaves. Here, a combination of transcriptomic and metabolic appr...
ORGANISM(S): Arabidopsis thaliana 
2015-09-02 | E-GEOD-71001 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially expressed genes in equine endometrium at day 8 and 12 of pregnancy
In order to systematically analyze the maternal, i.e. the endometrial, changes in the equine endometrium underlying the complex embryo-maternal dialogue during early pregnancy, a transcriptome study of endometrium samples from five mares at day 8 and six mares at day 12 of early pregnancy and the co...
ORGANISM(S): Equus caballus 
2010-06-30 | E-GEOD-21046 | biostudies-arrayexpress
TranscriptomicsPrion infected ScN2a and GT1
A comparison of prion infected and non-infected samples from neuroblastoma cells (N2a), and a comparison of prion infected and non-infected samples from hypothalmus cells (GT1). 11 dual-color DNA-chip hybridizations of cDNAs were made. Keywords: other
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-1803 | biostudies-arrayexpress
TranscriptomicsEpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth.
Introduction: The Epithelial Cell Adhesion Molecule (EpCAM) has been shown to be strongly expressed in human breast cancer and cancer stem cells and its overexpression has been supposed to support tumor progression and metastasis. However, effects of EpCAM overexpression on normal breast epithelial ...
ORGANISM(S): Homo sapiens 
2013-06-13 | E-GEOD-39071 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human IFN-Gamma treated keratinocytes
An experiment comparing control versus IFN-g treated skin cells (one design factor on two levels). To evaluate the biological and the experimental variability, the following experimental design was planned as shown in Figure 1: "Control" and "IFN-g stimulated" keratinocytes were cultured in triplica...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1132 | biostudies-arrayexpress
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