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TranscriptomicsGene expression profiling of LT-HSCs and ST-HSCs conditionally expressing MLL-ENL
We have developed a new conditional transgenic mouse showing that MLL-ENL, at an endogenous-like expression level, induces leukemic transformation selectively in LT-HSCs. To investigate the molecular mechanism of leukemic transformation in LT-HSCs conditionally expressing MLL-ENL, we preliminarily p...
ORGANISM(S): Mus musculus 
2013-07-17 | E-GEOD-48539 | biostudies-arrayexpress
TranscriptomicsThe nuclear actin-related protein Arp6 contributes to the radial positioning of chromosome territories.
The chromatin of individual chromosomes is organized into chromosome territories (CTs) in the interphase nucleus. The spatial arrangement of CTs is non-random and evolutionarily conserved. The gene-dense and gene-poor CTs are positioned in the nuclear center and periphery, respectively. As candidate...
ORGANISM(S): Gallus gallus 
2015-11-04 | E-GEOD-14220 | biostudies-arrayexpress
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