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TranscriptomicsRNA-seq of Brassica rapa leaves elicited with either Pseudomonas syringae pv. maculicola or flg22
Phytoalexins are abundant in edible crucifers and have important biological activities, yet no dedicated gene for their biosynthesis is known. Here, we report two new cytochromes P450 from the non-model plant Brassica rapa (Chinese cabbage) that catalyze unprecedented S-heterocyclizations in cyclobr...
ORGANISM(S): Brassica rapa subsp. pekinensis 
2015-09-21 | E-GEOD-69785 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Sorghum bicolor 9d seedlings in response to osmotic stress and abscisic acid
This study utilized next generation sequencing technology (RNA-Seq) to examine the transcriptome of sorghum plants challenged with osmotic stress and exogenous abscisic acid (ABA) to elucidate those genes and gene networks that contribute to sorghum's tolerance to water-limiting environments with a ...
ORGANISM(S): Sorghum bicolor 
2011-10-26 | E-GEOD-30249 | biostudies-arrayexpress
TranscriptomicsRNA-Seq and BS-Seq of Sorghum bicolor tissues
This study utilized next generation sequencing technology (RNA-Seq and BS-Seq) to examine the transcriptome and methylome of various tissues within sorghum plants with the ultimate goal of improving the Sorghum bicolor annotation We examined the mRNA of various Sorghum bicolor (BTx623) tissues (flow...
ORGANISM(S): Sorghum bicolor 
2014-08-29 | E-GEOD-50464 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
TranscriptomicsRNA-Seq and BS-Seq of Sorghum bicolor tissues
This experiment contains the subset of data corresponding to sorghum RNA-Seq data from experiment E-GEOD-50464 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-50464/), which goal is to examine the transcriptome of various Sorghum bicolor (BTx623) tissues: flowers, vegetative and floral meriste...
ORGANISM(S): Sorghum bicolor 
2014-08-29 | E-MTAB-3839 | biostudies-arrayexpress
MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
TranscriptomicsEstrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors
E2 exposure significantly decreased peak viral titer in hNECs from female donors. We used microarray analyses to identify global gene expression patterns between E2 and vehicle exposed hNECs from female donors Influenza causes an acute infection characterized by virus replication in respiratory epit...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-75208 | biostudies-arrayexpress
UnknownEvaluation of two frailty indices, with practical application in a vaccine clinical trial.
Not available
S-EPMC6930102 | biostudies-literature
GenomicsEGAS00001000515-sc-20141203 - samples
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAD00001001090 | EGA
GenomicsEGAS00001000603-sc-20140423 - samples
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAD00001000825 | EGA
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