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TranscriptomicsMaternal hematopoietic TNF, via milk chemokines, programs hippocampal development and memory
TNF is a proinflammatory cytokine with established roles in host defense and immune system organogenesis. Here we report a novel physiological function of TNF that extends its effect beyond the host into the developing offspring. A partial/complete maternal TNF-deficit, specifically in hematopoiet...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-52069 | biostudies-arrayexpress
GenomicsPropogation of anxiety-traits through the maternal line via parallel and segregated gametic and non-gametic epigenetic mechanisms
Maternal stress, anxiety, and depression increase the risk of psychiatric disorders in the progeny. These maternal effects can extend beyond the first generation and affect the grandchildren. In contrast to paternal, maternal effects can impact the offspring not only during gametogenesis, but also t...
ORGANISM(S): Mus musculus 
2016-04-04 | E-GEOD-68713 | biostudies-arrayexpress
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