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TranscriptomicsTranscription profiling of human embryonic kidney cells HEK293 overexpressing the transcription factors HNF4a2 or mutant forms HNF4a2 C106R and HNF4a2 R154X to identify HNF4a regulated genes in kidney cells being several of these genes deregulated in renal cell carcinoma
Analysis of gene expression in human embryonic kidney cells HEK293 overexpressing the transcription factors HNF4a2 or mutant forms HNF4a2 C106R and HNF4a2 R154X, which were introduced by FRT/FLP recombination. The analysis was performed 24 hours following 1sg/ml tetracycline treatment to induce the ...
ORGANISM(S): Homo sapiens 
2007-10-30 | E-GEOD-2700 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Rattus norvegicus pancreatic beta cell line expressing HNF1b, HNF4a2 or HNF6
This SuperSeries is composed of the following subset Series:; GSE1589: Targets of HNF1b, HNF4a2 and HNF6 in INS-1 cells; GSE1590: Targets of HNF1b mutants in INS-1; GSE1591: INS-1 cell lines (FLP-In T-REx) Experiment Overall Design: Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2007-11-29 | E-GEOD-6428 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat insulinoma INS-1 cell lines (FLP-In T-REx)
Four rat insulinoma cell lines (INS-1) were generated that contain a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the cell lines contain the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene e...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1591 | biostudies-arrayexpress
UnknownDistinct cytokine-driven responses of activated blood gammadelta T cells: insights into unconventional T cell pleiotropy.
Not available
S-EPMC3915340 | biostudies-literature
TranscriptomicsTranscription profiling of rat insulinoma line INS-1 to identify targets of HNF1b mutants in INS-1
A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1590 | biostudies-arrayexpress
UnknownBispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma.
Not available
S-EPMC10201273 | biostudies-literature
TranscriptomicsNFATc1 controls the survival, function and suppressive capacity of B lymphocytes upon B cell receptor stimulation
Triggering of B cell receptors (BCR) induces a massive synthesis of NFATc1 in splenic B cells. By inactivating the Nfatc1 gene and re-expressing NFATc1 we show that NFATc1 levels are critical for the survival of splenic B cells upon BCR stimulation. NFATc1 ablation led to decreased BCR-induced Ca++ ...
ORGANISM(S): Mus musculus 
2011-03-23 | E-GEOD-21063 | biostudies-arrayexpress
UnknownThe Use of Computerized Tomography Scans in Elective Knee and Hip Arthroplasty-What Do They Tell Us and at What Risk?
Not available
S-EPMC9095648 | biostudies-literature
UnknownPattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4alpha and HNF1beta in a pancreatic beta-cell line.
Not available
S-EPMC528820 | biostudies-literature
ProteomicsValosin-containing protein-regulated endoplasmic reticulum stress causes NOD2-dependent inflammatory responses
To detect novel NOD2 interaction partners in the context of IBD, immunoprecipitates from wildtype NOD2 and mutant NOD2 with IBD-causing variants were analyzed using LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2025-03-05 | PXD031539 | Pride
Human Nod2 Immunoprecipitation 
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