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UnknownmiR-125b regulates chemotaxis and survival of bone marrow derived granulocytes in vitro and in vivo.
Not available
S-EPMC6171867 | biostudies-literature
ProteomicsTracking chromatin state changes using nanoscale photo proximity labeling
Interactions between biomolecules underlie all cellular processes, and ultimately control cell fate. Perturbation of native interactions through mutation, changes in expression levels, or external stimuli leads to altered cellular physiology and can result in either disease or therapeutic effects. M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-19 | MSV000090929 | MassIVE
TranscriptomicsViral Expression and Molecular Profiling in Liver Tissue versus Microdissected Hepatocytes in Hepatitis B Virus - Associated Hepatocellular Carcinoma
The molecular mechanisms whereby hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) remain elusive. We used genomic and molecular techniques to investigate host-virus interactions by mapping the entire liver of patients with HCC. We compared the gene signature of whole liver tissue (WLT)...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-55092 | biostudies-arrayexpress
TranscriptomicsRole of Humoral Immunity against Hepatitis B Virus Core Antigen in the Pathogenesis of Acute Liver Failure
To investigate the role of viral and host factors in acute liver failure, we analyzed serum and multiple liver specimens obtained at the time of liver transplantation from four well-characterized patients. We carried out an integrated clinicopathological analysis, gene and microRNA expression profil...
ORGANISM(S): Homo sapiens 
2018-10-29 | E-GEOD-96851 | biostudies-arrayexpress
TranscriptomicsNon-alcoholic steatohepatitis causes selective CD4+ T cell loss and promotes hepatocarcinogenesis
Hepatocellular carcinoma (HCC) is the second most common cause of cancer related death. NAFLD affects a large proportion of the US population. Its incidence and prevalence are increasing to epidemic proportions around the world and is known to increase the risk of HCC. We studied how intrahepatic li...
ORGANISM(S): Mus musculus 
2016-03-10 | E-GEOD-67918 | biostudies-arrayexpress
TranscriptomicsIdentification of microRNAs specifically expressed in HCV-associated hepatocellular carcinoma
Background: Several studies have investigated the association of miRNAs with hepatocellular carcinoma (HCC) but the data are not univocal. Methods: We performed a microarray study of miRNAs in hepatitis C virus (HCV)-associated HCC and other liver diseases and healthy conditions. Results and Concl...
ORGANISM(S): Homo sapiens 
2013-02-20 | E-GEOD-40744 | biostudies-arrayexpress
UnknownVariable cellular responses to SARS-CoV-2 in fully vaccinated patients with multiple myeloma.
Not available
S-EPMC8523488 | biostudies-literature
UnknownAugmentation of humoral and cellular immune responses after third-dose SARS-CoV-2 vaccination and viral neutralization in myeloma patients.
Not available
S-EPMC8983835 | biostudies-literature
TranscriptomicsGene expression profile after TRPV4 knockdown in 3T3-F442A adipocytes
Comparing gene expression profile in 3T3-F442A adipocytes with shRNA against TRPV4 or GFP. TRPV4 is an ion channel expressed in adipocytes. Results provided information that how loss-of-function of TRPV4 affects gene expression in adipocytes. 4 samples were analyzed as two groups: shGFP (control) an...
ORGANISM(S): Mus musculus 
2012-10-12 | E-GEOD-40280 | biostudies-arrayexpress
UnknownType 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort.
Not available
S-EPMC12284355 | biostudies-literature
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