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TranscriptomicsTryptamine Serves As a Proligand of the AhR Transcriptional Pathway, and the Activation Is Dependent of Monoamine Oxidases
In this study we show that physiological concentrations of tryptamine (TA) lead to induction of cytochrome P4501A1 transcription through an AhR-dependent mechanism. In addition, we show that activation of the AhR by TA requires a functional monoamino oxidase system, suggesting that TA acts as an AhR...
ORGANISM(S): Mus musculus 
2012-08-02 | E-GEOD-39812 | biostudies-arrayexpress
TranscriptomicsPRRX1 transcription factor association to type 2 diabetes
Primary human adipose stromal cells (hASCs) from rs4684847 CC risk allele carriers were cultured and induced to differentiate into adipocytes, and simultaneously transfected for 72h with non-targeting siRNA or siRNA targeting PRRX1 (n=10) or both PRRX1 and PPARG (subset of the subjects, n=4).
ORGANISM(S): Homo sapiens 
2013-12-01 | E-MTAB-1906 | biostudies-arrayexpress
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