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TranscriptomicsFunctional genomics of human bronchial epithelial cells interacting with conidiospores of Aspergillus fumigatus
The cells of the airway epithelium play critical roles in host defense to inhaled irritants, and in asthma pathogenesis. These cells are constantly exposed to conidiospores of the ubiquitous mould Aspergillus fumigatus, which are small enough to reach the alveoli. This exposure is asymptomatic in mo...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-16628 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of interactions between Aspergillus fumigatus conidiospores and human bronchial epithelial cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Aspergillus fumigatus 
2011-06-01 | E-GEOD-16637 | biostudies-arrayexpress
TranscriptomicsFunctional genomics of Aspergillus fumigatus conidiospores interacting with human bronchial epithelial cells
The cells of the airway epithelium play critical roles in host defense to inhaled irritants, and in asthma pathogenesis. These cells are constantly exposed to conidiospores of the ubiquitous mould Aspergillus fumigatus, which are small enough to reach the alveoli. This exposure is asymptomatic in mo...
ORGANISM(S): Aspergillus fumigatus 
2011-06-01 | E-GEOD-16630 | biostudies-arrayexpress
TranscriptomicsDECREASED FIBRONECTIN PRODUCTION SIGNIFICANTLY CONTRIBUTES TO DYSREGULATED REPAIR OF ASTHMATIC EPITHELIUM
Rationale: Damage to airway epithelium is followed by deposition of extracellular matrix (ECM) and migration of adjacent epithelial cells. We have shown that epithelial cells from asthmatic children fail to heal a wound in vitro. Objectives: To determine whether dysregulated ECM production by the ep...
ORGANISM(S): Homo sapiens 
2010-04-12 | E-GEOD-18965 | biostudies-arrayexpress
TranscriptomicsA gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...
ORGANISM(S): Homo sapiens 
2012-09-11 | E-GEOD-27597 | biostudies-arrayexpress
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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