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ProteomicsCancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function (part 6: Mammary Fibroblasts Proteome)
Intercellular communication between different cell types in solid tumors contributes to tumor growth and metastatic dissemination. The secretome of cancer-associated fibroblasts (CAFs) plays major roles in these processes. Using human mammary CAFs, we unveil a mechanism of cell-cell communication be...
ORGANISM(S): Homo sapiens (Human) 
2024-02-16 | PXD049116 | Pride
Breast cancer Cancer-associated fibroblasts Extracellular vesicles Endothelial cells Mycafs Matrix-bound vesicles Intercellular protein transfer. 
ProteomicsCancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function (part 2: THP-1 proteome )
Intercellular communication between different cell types in solid tumors contributes to tumor growth and metastatic dissemination. The secretome of cancer-associated fibroblasts (CAFs) plays major roles in these processes. Using human mammary CAFs, we unveil a mechanism of cell-cell communication be...
ORGANISM(S): Homo sapiens (Human) 
2024-02-16 | PXD034460 | Pride
Breast cancer Cancer-associated fibroblasts Extracellular vesicles Endothelial cells Mycafs Matrix-bound vesicles Intercellular protein transfer. 
ProteomicsCancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function (part 5: pCAF1 proteome)
Intercellular communication between different cell types in solid tumors contributes to tumor growth and metastatic dissemination. The secretome of cancer-associated fibroblasts (CAFs) plays major roles in these processes. Using human mammary CAFs, we unveil a mechanism of cell-cell communication be...
ORGANISM(S): Homo sapiens (Human) 
2024-02-16 | PXD034573 | Pride
Breast cancer Cancer-associated fibroblasts Extracellular vesicles Endothelial cells Mycafs Matrix-bound vesicles Intercellular protein transfer. 
ProteomicsCancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function (part 3: Proteomic analysis of CM-EVs and MBVs secreted by pCAFs)
Intercellular communication between different cell types in solid tumors contributes to tumor growth and metastatic dissemination. The secretome of cancer-associated fibroblasts (CAFs) plays major roles in these processes. Using human mammary CAFs, we unveil a mechanism of cell-cell communication be...
ORGANISM(S): Homo sapiens (Human) 
2024-02-16 | PXD034467 | Pride
Breast cancer Cancer-associated fibroblasts Extracellular vesicles Endothelial cells Mycafs Matrix-bound vesicles Intercellular protein transfer. 
ProteomicsCancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function (part 1: Proteins transferred from cancer-associated fibroblasts to endothelial cells : trans-SILAC)
Intercellular communication between different cell types in solid tumors contributes to tumor growth and metastatic dissemination. The secretome of cancer-associated fibroblasts (CAFs) plays major roles in these processes. Using human mammary CAFs, we unveil a mechanism of cell-cell communication be...
2024-02-16 | PXD034450 | Pride
Breast cancer Cancer-associated fibroblasts Extracellular vesicles Endothelial cells Mycafs Matrix-bound vesicles Intercellular protein transfer. 
ProteomicsCancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function (part 4: Proteomic analysis of pCAFs expressing high and low α-SMA protein levels)
Intercellular communication between different cell types in solid tumors contributes to tumor growth and metastatic dissemination. The secretome of cancer-associated fibroblasts (CAFs) plays major roles in these processes. Using human mammary CAFs, we unveil a mechanism of cell-cell communication be...
ORGANISM(S): Homo sapiens (Human) 
2024-02-16 | PXD034519 | Pride
Breast cancer Cancer-associated fibroblasts Extracellular vesicles Endothelial cells Mycafs Matrix-bound vesicles Intercellular protein transfer. 
ProteomicsHypoxia-induced proteomic remodeling of human mammary cancer associated fibroblast - siRNA NCBP2-AS2
Intratumoral hypoxia causes the formation of dysfunctional blood vessels which contribute to tumor metastasis. Blood vessels are embedded in the tumor stroma where cancer-associated fibroblasts (CAFs) constitute the most prominent cellular component. We found that hypoxic human mammary CAFs promote ...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD006539 | Pride
Cancer Angiogenesis Hypoxia Silac Caf Proteome Secretome 
ProteomicsHypoxia-induced proteomic remodeling of human mammary cancer associated fibroblast
Intratumoral hypoxia causes the formation of dysfunctional blood vessels which contribute to tumor metastasis. Blood vessels are embedded in the tumor stroma where cancer-associated fibroblasts (CAFs) constitute the most prominent cellular component. We found that hypoxic human mammary CAFs promote ...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD006535 | Pride
Breast cancer  caf  proteomics  secretome  hypoxia  angiogenesis 
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
UnknownDeath following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
Not available
S-EPMC10364875 | biostudies-literature
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