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Neural stem cells (NSCs) generate neurons and glial cells throughout embryonic and postnatal brain development. The role of s-acylation, a reversible post-translational lipid modification of proteins, in regulating fate and activity of NSCs remains largely unknown. We here used an unbiased screening...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-27 | PXD014355 | Pride
Adult hippocampal neurogenesis is important for certain forms of cognition and failing neurogenesis has been implicated in neuropsychiatric diseases. The neurogenic capacity of hippocampal neural stem/progenitor cells (NSPCs) depends on a balance between quiescent and proliferative states. However, ...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-15 | PXD005598 | Pride
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