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TranscriptomicsGenotyping of human lung cancer cells on the 10K Affymetrix SNP array to validate whole genome amplification of genomic DNA from laser captured microdissectates and genotyping serial samples of developing lung cancers to identify early events
A series of experiments were performed to validate whole genome amplification of genomic DNA from laser captured microdissectates and the technique was then applied to serial samples of developing lung cancers to identify early events. 10K Affymetrix SNP arrays were used.
ORGANISM(S): Homo sapiens 
2006-10-01 | E-TABM-134 | biostudies-arrayexpress
UnknownLow-volume versus high-volume initiated trans-anal irrigation therapy in adults with chronic constipation: study protocol for a randomised controlled trial.
Not available
S-EPMC5374566 | biostudies-literature
ProteomicsProteasome-dependent protein degradation shapes developmental tempo in mouse and human neural progenitors
underlying molecular mechanisms remain poorly understood. To investigate the basis for species-specific developmental tempos, we performed a comprehensive comparative analysis of protein dynamics in mouse and human neural progenitors (NPs). Through a combination of targeted protein labelling, quanti...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-07-15 | PXD054152 | Pride
Human Neural progenitor Degradation Mouse Proteasome Lc-ms/ms 
UnknownLow levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids.
Not available
S-EPMC10588792 | biostudies-literature
UnknownAnalysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.
Not available
S-EPMC5384872 | biostudies-literature
UnknownPlasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation.
Not available
S-EPMC8850689 | biostudies-literature
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
UnknownGenome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2.
Not available
S-EPMC3296486 | biostudies-literature
UnknownUrinary Leukotriene E<sub>4</sub> and Prostaglandin D<sub>2</sub> Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study.
Not available
S-EPMC7781128 | biostudies-literature
UnknownLarge-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.
Not available
S-EPMC5789458 | biostudies-literature
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