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MetabolomicsMetabolomic profiling of primary mouse proximal tubule cells (mPTCs) derived from 24-week-old CTR and Atg7 PT-KO kidneys
To explore the role of ATG7 in the kidney PT, we crossed mice homozygous for floxed alleles of Atg7 with Ggt1-Cre mice expressing Cre recombinase under the rat Ggt1 (gamma-glutamyltransferase 1) gene promoter. This generated Atg7fl/fl; γGt1cre/cre mice (hereafter referred to as Atg7 PT-KO), in which...
2026-09-30 | MTBLS15857 | MetaboLights
GenomicsAnalysis of Wild Type, H-NS KO and cover mutated H-NS Transcriptomes
Analysis of Wild Type, H-NS KO and cover mutated H-NS Transcriptomes
PRJNA716815 | ENA
TranscriptomicsType-I interferon inducible genes 26 weeks after mCMV infection in Siglec-H wt and Siglec-H ko mice and their non infected controls
Type I interferons are critical anti-viral cytokines during virus infections and have also been implicated in the pathogenesis of systemic lupus erythematosus (SLE). The secretion of type I interferon of pDCs is modulated by Siglec-H, a DAP12 associated receptor on pDCs. We showed that Siglec-H defi...
ORGANISM(S): Mus musculus 
2016-03-16 | E-GEOD-79248 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver regeneration in Socs3 h-KO mice, Socs3 fl/fl, Alb-Cre- littermates controls
Suppressor of cytokine signaling 3 (SOCS3) down-regulates several signaling pathways in multiple cell types, and previous data suggest that SOCS3 may shut off cytokine activation at the early stages of liver regeneration. We developed hepatocyte-specific Socs3 knockout (Socs3 h-KO) mice to directly ...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9549 | biostudies-arrayexpress
TranscriptomicsAnalysis of Wild Type, H-NS KO and cover mutated H-NS Transcriptomes
The goals of this study are to compare the difference transcriptome of Wild Type, H-NS KO and cover mutated H-NS by RNA-seq
ORGANISM(S): Escherichia coli K-12 
2021-03-25 | GSE169499 | GEO
TranscriptomicsCondensin plays a role in both interphase nuclei and premature chromosome condensation
Purpose: to identify how condensin I removal affects gene expression globally. Methods: Chicken DT40 CAP-H KO cells were treated with or without dox for 36 h. Total RNA samples were extracted and subjected to sequencing using an Illumina Hiseq2000 platform. Library preparation and Illumina sequencin...
ORGANISM(S): Gallus gallus 
2017-05-03 | E-GEOD-74892 | biostudies-arrayexpress
GenomicsATAC-seq Analysis in Control and Mier1 KO Mice Liver at 0 h and 24 h after 70% Partial Hepatectomy
ATAC-seq Analysis in Control and Mier1 KO Mice Liver at 0 h and 24 h after 70% Partial Hepatectomy
PRJNA876292 | ENA
GenomicsHepatic Gene Expression Induced by CREB-H-ΔTC
Hepatic Gene Expression Induced by CREB-H-ΔTC
PRJNA1033554 | ENA
GenomicsSpatial transcriptomics of adipocyte-specific ATGL-KO mice 24 h after cardiac ischemia
Spatial transcriptomics of adipocyte-specific ATGL-KO mice 24 h after cardiac ischemia
PRJEB108100 | ENA
TranscriptomicsType-I interferon inducible genes 26 weeks after mCMV infection in Siglec-H wt and Siglec-H ko mice and their non infected controls
Type I interferons are critical anti-viral cytokines during virus infections and have also been implicated in the pathogenesis of systemic lupus erythematosus (SLE). The secretion of type I interferon of pDCs is modulated by Siglec-H, a DAP12 associated receptor on pDCs. We showed that Siglec-H defi...
ORGANISM(S): Mus musculus 
2016-03-16 | GSE79248 | GEO
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