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TranscriptomicsGlobal transcriptomic profiles of blood monocytes from Hmox1 homozygous knockout mice compared to wild type controls following Mtb infection
Since whole blood transcriptome profiling has been proposed as a reliable measure of immune responses in TB patients and because the plasma levels of HO-1 have been suggested as a potential TB diagnostic marker, we wanted to see the differences in the global transcriptomic profiles and the downstrea...
ORGANISM(S): Mus musculus 
2019-03-05 | E-MTAB-7221 | biostudies-arrayexpress
ProteomicsDifferential complexome profiling of CRISTA WT and KO HEK293T mitochondria
CRISTA (SMIM26) is a mitochondrial microprotein important for assembly of complex I. Here we used differential complexome profiling to study the composition of ETC complexes in SMIM26 WT and KO HEK293T mitochondria. CRISTA potentiates mitochondrial serine import via direct interactions with the seri...
ORGANISM(S): Homo sapiens (Human) 
2025-06-18 | PXD047664 | Pride
Microproteins Complexome profiling Complex i Mitochondria Supercomplexes 
ProteomicsComplexome profiling of BRAWNIN KO mouse heart mitochondria
BRAWNIN (BR) is a mitochondrial microprotein important for assembly of complex III. Here we used complexome to study the composition of supercomplexes in BR KO mouse heart mitochondria. BR deficiency induces the formation of a higher order electron transport chain complex which we renamed as extra-l...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-08 | PXD044957 | Pride
Microproteins Complexome profiling Mitochondria Supercomplexes 
TranscriptomicsTranscription profiling of yeast cells (homozygous deletion mutants of BY4743) grown in chemostats, sampled at steady state. Glucose and ammonium limitation, dilution rates 0.1 and 0.2 hr-1, gene deletions HO and HAP4 applied
S. cerevisiae cells (homozygous deletion mutants of BY4743) grown in chemostats, sampled at steady state. Glucose and ammonium limitation, dilution rates 0.1 and 0.2 hr-1, gene deletions HO and HAP4 applied.
ORGANISM(S): Saccharomyces cerevisiae 
2005-12-31 | E-MEXP-442 | biostudies-arrayexpress
UnknownRecipient HO-1 inducibility is essential for posttransplant hepatic HO-1 expression and graft protection: From bench-to-bedside.
Not available
S-EPMC6349504 | biostudies-literature
UnknownMyeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury.
Not available
S-EPMC6237471 | biostudies-literature
UnknownDexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway.
Not available
S-EPMC8027777 | biostudies-literature
UnknownScrophularia koraiensis Nakai Attenuates Allergic Airway Inflammation via Suppression of NF-κB and Enhancement of Nrf2/HO-1 Signaling.
Not available
S-EPMC7070852 | biostudies-literature
ProteomicsCo-administration of angiotensin II and simvastatin triggers kidney injury upon heme oxygenase-1 deficiency
Kidneys are pivotal organ in iron redistribution and can be severely damaged in the course of hemolysis. In our previous studies, we observed that induction of hyper- tension with angiotensin II (Ang II) combined with simvastatin administration results in a high mortality rate or the appearance of s...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-19 | PXD042995 | Pride
Kidney Angiotensin ii 
UnknownKuwanon T and Sanggenon a Isolated from Morus alba Exert Anti-Inflammatory Effects by Regulating NF-κB and HO-1/Nrf2 Signaling Pathways in BV2 and RAW264.7 Cells.
Not available
S-EPMC8708433 | biostudies-literature
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