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TranscriptomicsParalogous MarR/DUF24-family repressors YodB and CatR control expression of the catechol dioxygenase CatE in Bacillus subtilis
The redox-sensing MarR/DUF24-type repressor YodB controls expression of the azoreductase AzoR1 and the nitroreductase YodC that are involved in detoxification of quinones and diamide in Bacillus subtilis. In the present paper, we identified YodB and its paralog YvaP (CatR) as repressors of the yfiDE...
ORGANISM(S): Bacillus subtilis 
2010-06-29 | E-GEOD-22603 | biostudies-arrayexpress
UnknownDevelopment of Low-Molecular-Weight Compounds Targeting the Cancer-Associated KLF5 Transcription Factor.
Not available
S-EPMC9014505 | biostudies-literature
TranscriptomicsTracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells (cell culture)
Rabbit embryos, as in humans, develop as bilaminar discs at gastrulation and unlike egg cylinders as in rodents. Mammalian primordial germ cells (PGCs) in all species originate during gastrulation. We sequence the transcriptomes of rabbit embryos during gastrulation, and show that rabbit PGC (rbPGC...
ORGANISM(S): Oryctolagus cuniculus 
2021-10-14 | E-MTAB-10893 | biostudies-arrayexpress
TranscriptomicsTracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells (bulk RNA-sequencing)
Rabbit embryos, as in humans, develop as bilaminar discs at gastrulation and unlike egg cylinders as in rodents. Mammalian primordial germ cells (PGCs) in all species originate during gastrulation. We sequence the transcriptomes of rabbit embryos during gastrulation, and show that rabbit PGC (rbPGC...
ORGANISM(S): Oryctolagus cuniculus 
2021-10-14 | E-MTAB-10892 | biostudies-arrayexpress
TranscriptomicsExpression profiles of 186-gene signature in U.S. hepatitis C virus (HCV)-related liver cirrhosis
OBJECTIVE: The number of patients with HCV-related cirrhosis is increasing, leading to a rising risk of complications and death. Prognostic stratification in patients with early-stage cirrhosis is still challenging. We aimed to develop and validate a clinically useful prognostic index based on genom...
ORGANISM(S): Homo sapiens 
2014-08-22 | E-GEOD-54100 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic kidney in Lim1 conditional mutant mice
Microarray experiment on each time point and genotype was performed in technical duplicates (ie. a single RNA preparation of pooled kidneys of one genotype used for two separate target preparations). Data from a total of 8 independent arrays were used in this study, 2 arrays were used for RNA sample...
ORGANISM(S): Mus musculus 
2007-12-15 | E-GEOD-4230 | biostudies-arrayexpress
TranscriptomicsWhy nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
Why nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
ORGANISM(S): Homo sapiens 
2014-08-01 | E-MTAB-1290 | biostudies-arrayexpress
TranscriptomicsIdentification of genes that are regulated by the A and B isoforms of the human progesterone receptor
T47D breast cancer cells were used for this microarray gene expression study. case vs control
ORGANISM(S): Homo sapiens 
2010-03-04 | E-GEOD-18276 | biostudies-arrayexpress
TranscriptomicsSingle cell transcriptional profiling of mouse molar and incisor tooth assembloids
Throughout the various stages of tooth development, reciprocal epithelial-mesenchymal interactions are the driving force, for instance crucially involved in the differentiation of mature enamel-forming ameloblasts and dentin-producing odontoblasts. Here we established mouse tooth ‘assembloids’, comp...
ORGANISM(S): Mus musculus 
2023-04-19 | E-MTAB-12544 | biostudies-arrayexpress
TranscriptomicsNCH_SLK_GBM_Predonisolone
Animals: Specific pathogen-free male Wistar-Kyoto rats weighing 300 to 350 g (Charles River Japan, Kanagawa, Japan) were used. Experiments were performed according to institutional guidelines. Anti-GBM GN: GBM antigen for the rats was prepared as described previously(1,2). Five albino rabbits were i...
ORGANISM(S): Rattus norvegicus 
2010-06-05 | E-GEOD-1262 | biostudies-arrayexpress
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