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UnknownSurface charge density measurement of a single protein molecule with a controlled orientation by AFM.
The spatial distribution of functional groups causes a charge distribution that often has a close relationship with its biofunctions. To understand them of the protein molecules, measurements of the charge distribution under physiological conditions are desired. Atomic force microscopy (AFM) has bee...
S-EPMC8390862 | biostudies-literature
UnknownMolecular-scale visualization and surface charge density measurement of Z-DNA in aqueous solution.
The DNA in the left-handed conformation (Z-conformation) was first discovered by A. Rich, who revealed the crystalline structure of a DNA oligomer d(GC)3 by X-ray diffraction method. Later it was also found that DNA molecules change their conformations from typical right-handed form (B-DN...
S-EPMC6497900 | biostudies-literature
UnknownVisualization of Au Nanoparticles Buried in a Polymer Matrix by Scanning Thermal Noise Microscopy.
Several researchers have recently demonstrated visualization of subsurface features with a nanometer-scale resolution using various imaging schemes based on atomic force microscopy. Since all these subsurface imaging techniques require excitation of the oscillation of the cantilever and/or sample su...
S-EPMC5314356 | biostudies-literature
UnknownLumbar ligamentum flavum hematoma at L3-4 treated with full-endoscopic laminectomy: a case report.

Background

Lumbar ligamentum flavum hematoma (LFH) is a rare cause of nerve root and/or cauda equina compression which is commonly treated using microsurgical laminectomy and posterior fixation. However, technological advances may allow for less invasive options to be used.

Case descripti...

S-EPMC12516574 | biostudies-literature
UnknownDevelopment of a Novel Tetravalent Synthetic Peptide That Binds to Phosphatidic Acid.
We employed a multivalent peptide-library screening technique to identify a peptide motif that binds to phosphatidic acid (PA), but not to other phospholipids such as phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylserine (PS). A tetravalent peptide with the sequence motif o...
S-EPMC4493020 | biostudies-literature
UnknownProtein nanoarrays using the annexin A5 two-dimensional crystal on supported lipid bilayers.
Protein nanoarrays are regularly ordered patterns of proteins fixed on a solid surface with a periodicity on the order of nanometers. They have significant potential applications as highly sensitive bioassays and biosensors. While several researchers have demonstrated the fabrication of protein nano...
S-EPMC10368004 | biostudies-literature
UnknownOral mucositis associated with anti-EGFR therapy in colorectal cancer: single institutional retrospective cohort study.

Background

Chemotherapy-induced oral mucositis impairs the quality of life. The difference in severity of oral mucositis between different anti-epidermal growth factor receptor (EGFR) antibodies combined with cytotoxic drugs in colorectal cancer is unclear. The aim of this study was to inves...
S-EPMC6173836 | biostudies-literature
UnknownFundamental and higher eigenmodes of qPlus sensors with a long probe for vertical-lateral bimodal atomic force microscopy.
The detection of vertical and lateral forces at the nanoscale by atomic force microscopy (AFM) reveals various mechanical properties on surfaces. The qPlus sensor is a widely used force sensor, which is built from a quartz tuning fork (QTF) and a sharpened metal probe, capable of high-resolution ima...
S-EPMC9890686 | biostudies-literature
UnknownImmunoactivity of self-assembled antibodies investigated by atomic force microscopy.
Immunoglobulin G (IgG), an antibody, plays a significant role in the immune system, and the functions of IgG molecules have been studied in many research fields such as medicine and engineering. Recently, we found the self-assembly of monoclonal mouse IgG molecules on a mica substrate using atomic f...
S-EPMC9084463 | biostudies-literature
UnknownPalatability and Bio-Functionality of Chalky Grains Generated by High-Temperature Ripening and Development of Formulae for Estimating the Degree of Damage Using a Rapid Visco Analyzer of Japonica Unpolished Rice.
Global warming inhibits grain filling in rice and leads to chalky grains, which are damaged in physical and cooking qualities. In the present paper, we evaluated 54 Japonica unpolished rice grains harvested in Japan in 2020, and these samples (original grains) were divided to two groups (whol...
S-EPMC9658192 | biostudies-literature
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