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TranscriptomicsComparative analysis of gene expression profiles between four kinds of blastomere at 8-cell stage embryos.
The establishment of body axes and specification of early embryonic cells depend on maternally supplied transcripts and/or proteins, several of which are localized at specific regions of fertilized eggs and early embryos. The ascidian is known to exhibit a mosaic mode of development, and this mode ...
ORGANISM(S): Ciona intestinalis 
2010-06-19 | E-GEOD-15637 | biostudies-arrayexpress
TranscriptomicsNovel Lipogenic Enzyme ELOVL7 Involves in Prostate Cancer Growth through Saturated Fatty-acid and Steroid Metabolism
We identified a novel lipogenic gene, ELOVL7, as an over-expressed gene in prostate cancer (PC) cells and it is involved in elongation of long-chain fatty acids and can play some important roles in prostate carcinogenesis. To investigate into downstream pathways of ELOVL7, we performed the gene expr...
ORGANISM(S): Homo sapiens 
2009-04-01 | E-GEOD-14852 | biostudies-arrayexpress
TranscriptomicsIntegrative Transcriptome Analysis Reveals Common Molecular Subtypes of Human Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to develop genomic-based classification for HCC have yielded highly divergent results, indicating difficulty in identifying unified molecular anatomy. We performed a meta-analysis of gene expression profiles in data...
ORGANISM(S): Homo sapiens 
2009-09-08 | E-GEOD-10186 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models [Affymetrix]
Cardiovascular complications are the leading cause of death in autosomal dominant polycystic kidney disease (ADPKD), and intracranial aneurysm (ICA) causing subarachnoid hemorrhage is among the most serious complications. The diagnostic and therapeutic strategies for ICAs in ADPKD have not been full...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74452 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models [Agilent]
Cardiovascular complications are the leading cause of death in autosomal dominant polycystic kidney disease (ADPKD), and intracranial aneurysm (ICA) causing subarachnoid hemorrhage is among the most serious complications. The diagnostic and therapeutic strategies for ICAs in ADPKD have not been full...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74451 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Training Set, Liver)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-10140 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Training Set, HCC)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-10141 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Validation Set)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-10142 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-20 | E-GEOD-10143 | biostudies-arrayexpress
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