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UnknownComparative study of the inhibitory effect on bone erosion progression with denosumab treatment and conventional treatment in rheumatoid arthritis patients: study protocol for an open-label randomized controlled trial by HR-pQCT.
Not available
S-EPMC6691552 | biostudies-literature
UnknownDopamine error signal to actively cope with lack of expected reward.
Not available
S-EPMC10005178 | biostudies-literature
UnknownInhibition of bone erosion, determined by high-resolution peripheral quantitative computed tomography (HR-pQCT), in rheumatoid arthritis patients receiving a conventional synthetic disease-modifying anti-rheumatic drug (csDMARD) plus denosumab vs csDMARD therapy alone: an open-label, randomized, parallel-group study.
Not available
S-EPMC9727996 | biostudies-literature
UnknownPrognostic significance of IMMT expression in surgically-resected lung adenocarcinoma.
Not available
S-EPMC6825906 | biostudies-literature
TranscriptomicsMepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
For the clinical treatment of chronic obstructive pulmonary disease (COPD), it is important not only to improve the airflow limitation by bronchodilation but also to suppress emphysema by controlling inflammation. In this study, we have screened for compounds that prevent elastase-induced airspace ...
ORGANISM(S): Mus musculus 
2013-11-13 | E-GEOD-50836 | biostudies-arrayexpress
UnknownMolecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.
Not available
S-EPMC6525482 | biostudies-literature
TranscriptomicsSignificance of SALL4 as a drug resistant factor in lung cancer
To examine the mechanism by which SALL4 regulates drug sensitivity, approximately 65,000 molecules on a microarray chip were analyzed using lung cancer cells transduced with a SALL4 vector (pCMV6-SALL4) or a control vector (pCMV6-Mock) . SALL4 mRNA and protein expression markedly increased after 24 ...
ORGANISM(S): Homo sapiens 
2014-04-30 | E-GEOD-56595 | biostudies-arrayexpress
UnknownFetal reversion from diverse lineages sustains the intestinal stem cell pool and confers stress resilience.
Not available
S-EPMC12909903 | biostudies-literature
TranscriptomicsIdentification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model
More effective therapeutic approaches for castration-resistant prostate cancer (CRPC) are urgently needed, thus reinforcing the need to understand how prostate tumors progress to castration resistance. We have established a novel mouse xenograft model of prostate cancer, KUCaP-2, which expresses the...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-21887 | biostudies-arrayexpress
TranscriptomicsIdentification of a novel risk factor for intracranial aneurysms in ADPKD using iPSC models [Affymetrix]
Cardiovascular complications are the leading cause of death in autosomal dominant polycystic kidney disease (ADPKD), and intracranial aneurysm (ICA) causing subarachnoid hemorrhage is among the most serious complications. The diagnostic and therapeutic strategies for ICAs in ADPKD have not been full...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-74452 | biostudies-arrayexpress
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