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UnknownGigaSOM.jl: High-performance clustering and visualization of huge cytometry datasets.
Not available
S-EPMC7672468 | biostudies-literature
ProteomicsStrength of a “single-tube” protocol for protein isolation from multiple cell fractions shown for the plant pathogen Xanthomonas campestris pv. campestris B100 with a focus on proteins involved in the biosynthesis of the exopolysaccharide xanthan
Xanthomonas campestris pv. campestris (Xcc) B100 is a phytopathogenic bacterium, which uses xanthan, a secreted heterogeneous exopolysaccharide in both stages of infection of Brassicaceae. Until now, proteome analysis of Xcc lacking a detailed view on the proteins involved in xanthan biosynthesis. P...
ORGANISM(S): Xanthomonas campestris pv. campestris str. B100 
2022-02-16 | PXD027261 | Pride
“single-tube” protocol  lfq analysis  multiple cell fraction analysis  xanthomonas campestris - xanthan biosynthesis  qexactive plus 
ProteomicsMuscle stem cell maintenance and regeneration of skeletal muscle require functional motor innervation
Background: Skeletal muscle crucially depends on motor innervation, and, when damaged, on the resident muscle stem cells (MuSCs). However, the role and function of MuSCs in the context of denervation remains poorly understood. Methods: Alterations of MuSCs and their myofiber niche after denervation...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-27 | PXD036993 | Pride
Muscle stem cell Motor innervation Skeletal muscle Denervation Myofibers 
TranscriptomicsComparison of stimulatory and inhibitory dendritic cell subsets reveals new role of DC in granulomatous infection
Myeloid dendritic cells (DC) and macrophages play an important role in pathogen sensing and antimicrobial defense. Recently we demonstrated that infection of human DC with intracellular bacterium Listeria monocytogenes (L.monocytogenes) leads to the induction of the immunoinhibitory enzyme indoleami...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-9946 | biostudies-arrayexpress
UnknownProficiency Testing of Metagenomics-Based Detection of Food-Borne Pathogens Using a Complex Artificial Sequencing Dataset.
Not available
S-EPMC7672002 | biostudies-literature
TranscriptomicsIpsA, a novel transcriptional regulator required for inositol derived lipid formation in Corynebacteria and Mycobacteria
The development of new drugs against tuberculosis and diphtheria is focused on disrupting the biogenesis of the cell wall, the unique architecture of which confers resistance against current therapies. The enzymatic pathways involved in the synthesis of the cell wall by these pathogens are well unde...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2014-01-13 | E-GEOD-50210 | biostudies-arrayexpress
Proteomics,MultiomicsSNW1 is required for sister chromatid cohesion
Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hum...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-02 | MSV000080878 | MassIVE
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Full Proteomes
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081738 | MassIVE
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CPTAC Full Proteomes
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081739 | MassIVE
ProteomicsPharmacoproteomic characterisation of human colon and rectal cancer - CRC65 Kinobeads
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models are only beginning to emerge. Here, we profiled the proteomes of 65 colorectal cancer (CRC) cell lines to a depth of >10,000 proteins using mass spectrometry. Integration with prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-23 | MSV000081735 | MassIVE
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