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ProteomicsProteome Profiling in Cerebrospinal Fluid Reveals Novel Biomarkers of Alzheimer’s Disease
Neurodegenerative diseases are a growing burden and there is an urgent need for better biomarkers for diagnosis, prognosis and treatment efficacy. Structural and functional brain alterations are reflected in the protein composition of cerebrospinal fluid (CSF). Alzheimer’s disease (AD) patients ha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-01-06 | MSV000088649 | MassIVE
TranscriptomicsGene Transcription Abnormalities in Canine Atopic Dermatitis
Canine atopic dermatitis (AD) is clinically similar to human AD, implicating it as a useful model of human eosinophilic allergic disease. To identify cutaneous gene transcription changes in relatively early inflammation of canine AD, microarrays were used to monitor transcription in normal skin (n=...
ORGANISM(S): Canis lupus familiaris 
2012-07-11 | E-GEOD-39278 | biostudies-arrayexpress
ProteomicsQuantitative proteomic approach identifies Vpr binding protein as novel host factor supporting influenza A virus infections in human cells
Influenza A virus infections are a major cause for respiratory disease in humans, which affects all age groups and contributes substantially to global morbidity and mortality. IAV have a large natural host reservoir in avian species. However, many avian IAV strains lack adaptation to other hosts and...
ORGANISM(S): Homo sapiens (Human) 
2017-03-14 | PXD005825 | Pride
Influenza Quantitative proteomics Vprbp 
ProteomicsH.sapiens - Cell line, Hct116 (Koch,proteomics,2014)
abundance based on MAPPED_BY_AUTHORS, HCT116, Interaction consistency score: 4.6, Coverage: 5
ORGANISM(S): 9606 
2014-00-00 | 1430705385 | PAXDB
UnknownSystematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State.
Not available
S-EPMC9532381 | biostudies-literature
UnknownLessons learned from phase 3 trials of immunotherapy for glioblastoma: Time for longitudinal sampling?
Not available
S-EPMC10836778 | biostudies-literature
UnknownHuman cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation
Not available
S-SCDT-EMBOR-2021-54027-T | biostudies-other
TranscriptomicsThe tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
The histone modifying complexes PRC2 and TrxG/MLL play pivotal roles in determining the activation state of genes controlling pluripotency, lineage commitment, and cell differentiation. Long non-coding RNAs (lncRNAs) can bind to either complex, and some have been shown to act as modulators of PRC2 o...
ORGANISM(S): Mus musculus 
2013-01-28 | E-GEOD-43078 | biostudies-arrayexpress
UnknownLimited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.
Not available
S-EPMC7483776 | biostudies-literature
ProteomicsBreeding from 1891 to 2010 did not increase the content of amylase/trypsin-inhibitors in wheat (Triticum aestivum L.)
The prevalence of hypersensitivities towards wheat has increased in the last decades. Apart from celiac disease these include allergic and other inflammatory reactions summarized under the term non-celiac wheat sensitivity. One suspected trigger is the family of amylase/trypsin-inhibitors (ATIs), no...
ORGANISM(S): Triticum Aestivum 
PXD043968 | panorama
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