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TranscriptomicsRole of TTF-1/NKX2-1, Smad3 and Smad4 on lung cancer cell lines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-51510 | biostudies-arrayexpress
GenomicsSmad3, Smad4 and TTF-1/NKX2-1 binding sites in H441/A549 lung cancer cell lines
We evaluated the role of TTF-1/NKX2-1 on Smad3 and Smad4 binding in lung cancer cell lines. Smad3 binding sites in A549 cells and Smad3, Smad4, and TTF-1/NKX2-1 binding sites in H441 cells were determined by ChIP-seq.
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-51509 | biostudies-arrayexpress
GenomicsSMAD1/5 binding regions of human umbilical vein endothelial cells (HUVECs) treated with BMP.
Smad1/5 binding regions were identified by ChIP-seq. HUVECs were treated with BMP for 1.5 h and anti-SMAD1/5 ChIP-seq analyses were performed using Illumina genome analyzer.
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-27634 | biostudies-arrayexpress
GenomicsHNF4A-binding sites in HepG2 hepatoblastoma cells treated with TGF-beta
Specific regulation of target genes by transforming growth factor-β (TGF-β) in a given cellular context is determined in part by transcription factors and cofactors that interact with the Smad complex. In the present study, we determined Smad2 and Smad3 (Smad2/3) binding regions in the promoters of ...
ORGANISM(S): Homo sapiens 
2011-06-08 | E-GEOD-28845 | biostudies-arrayexpress
UnknownRandom mutagenesis-based screening of the interface of phyllogen, a bacterial phyllody-inducing effector, for interaction with plant MADS-box proteins.
Not available
S-EPMC10086140 | biostudies-literature
UnknownTuneable pressure effects in graphene oxide layers.
Not available
S-EPMC5610342 | biostudies-literature
TranscriptomicsExpression data from normal murine mammary epithelial cell line NMuMG stimulated with TGF-beta
TGF-beta is one of the most important cytokines that induce epithelial to mesenchymal transition (EMT). In this dataset, we examined TGF-beta induced changes in gene and exon level expression. Core probesets of two samples were analyzed. NMuMG cells were stimulated with TGF-beta for 24 h or left unt...
ORGANISM(S): Mus musculus 
2011-11-01 | E-GEOD-28184 | biostudies-arrayexpress
UnknownSerum caffeine and metabolites are reliable biomarkers of early Parkinson disease.
Not available
S-EPMC5791797 | biostudies-literature
TranscriptomicsExpression data of human lung adenocarcinoma cell line H441 treated with TTF-1/NKX2-1 siRNA and TGF-beta
We determined and analyzed the effect of TTF-1/NKX2-1 on Smad3/Smad4 binding sites by ChIP-sequencing. We used expression microarrays to evaluate the effect of TTF-1/NKX2-1 siRNA on TGF-beta-induced gene expressions. H441 cells were transfected with siRNAs and treated with TGF-beta for RNA extractio...
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-49675 | biostudies-arrayexpress
TranscriptomicsEffect of TTF-1/NKX2-1 expression on TGF-beta induced gene expression in A549 lung cancer cell line.
TTF-1/NKX2-1 was expressed by adenoviral vector and changes in gene expression were determined by RNA-sequencing. A549 cells were infected with Ad-TTF-1 or Ad-LacZ vectors and stimulated with TGF-beta for 24 hours or left untreated. Expression of polyA RNA was determined.
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-56356 | biostudies-arrayexpress
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