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Background: The acquisition of drug resistance is one of the most malignant phenotypes of cancer. MicroRNAs (miRNAs) have been implicated in various types of cancers, but its role in taxane-resistance of prostate cancer remains poorly understood. Methods: In order to identify miRNAs related to taxan...
ORGANISM(S): Homo sapiens 
Background: The acquisition of drug resistance is one of the most malignant phenotypes of cancer. MicroRNAs (miRNAs) have been implicated in various types of cancers, but its role in taxane-resistance of prostate cancer remains poorly understood. Methods: In order to identify miRNAs related to taxan...
ORGANISM(S): Homo sapiens 
To investigate effects of intake of Eucommia ulmoides leaves on hyperlipidemia, we performed gene expression profiling on rat liver by microarray analysis. Microarray analysis revealed that Eucommia ulmoides leaves up-regulated the gene expression involved in alpha-, beta-, and omega-oxidation of fa...
ORGANISM(S): Rattus norvegicus 
Transcriptional changes of an Arabidopsis mutant, pasticcino2 (pas2).
ORGANISM(S): Arabidopsis thaliana 
To investigate effects of intake of mulberry leaf extracts on hypercholesterolemia, we performed gene expression profiling on rat liver by microarray analysis. Microarray analysis revealed that mulberry leaf extracts up-regulated the gene expression involved in suppression of cholesterol synthesis a...
ORGANISM(S): Mus musculus 
To identify a biomarker that can predict the response of preoperative chemoradiotherapy (PCRT). Twenty-five serum samples from patents with esophageal cancer before PCRT (responder = 13, non-responder = 12) were analyzed by quantitative proteomics.
ORGANISM(S): Homo Sapiens (human) 
Piwi-interacting RNAs are 25-32 nt small RNAs bound to Piwi proteins. To know the steps where factors involved in the piRNA biogenesis (MILI, MIWI2, ZUC (MitoPLD), MVH) work, we sequenced small RNAs from mutant mouse testes and analyzed piRNAs. Examination of small RNAs in testes of mutant mouse
ORGANISM(S): Mus musculus 
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