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ProteomicsGamma ray irradiation of epithelial carcinoma cells under hypoxic conditions
We demonstrate for the first time that under hypoxic conditions, A431 epithelial carcinoma cells exhibit increased viability when exposed to low-dose ?-irradiation, indicating that radiotherapy can promote tumor cell survival when oxygen supply is limited. When assessed using iTRAQ quantitative prot...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080784 | MassIVE
OtherExtracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR).
Data from ProteomeXchange, PXD ID: PXD002668. File: UltraCushion_R1_28.mzml. Published as part of Sci Rep. 2015 Sep 30;5:14664 . From the Abstract: {{i}} Extracellular vesicles (EVs) such as exosomes and microvesicles mediate intercellular communication and regulate a diverse range of crucial biolo...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310024861 | GPMDB
Resource Reanalysis 
TranscriptomicsA Distinct Reactive Oxygen Species Profile confers Chemoresistance in Glioma-Propagating Cells and Associates with Patient Survival Outcome
Aims: We explore the role of elevated O2-:H2O2 ratio as a prosurvival signal in glioma-propagating cells (GPCs). We hypothesize that depleting this ratio sensitizes GPCs to apoptotic triggers. Results: We observed that elevated O2-:H2O2 ratio conferred enhanced resistance in GPCs, and depletion of t...
ORGANISM(S): Homo sapiens 
2013-03-13 | E-GEOD-32335 | biostudies-arrayexpress
ProteomicsArtificial intelligence defines protein-based classification of thyroid nodules
We applied PCT-DIA on a total of 1161 nodules from 1133 patients using either tissue cores (1 mm diameter; 0.5–1 mm depth) punched from regions of interest marked on retrospective FFPE tissue blocks or prospective cytology specimens from FNA aspirates. The samples comprise (i) a discovery set of FFP...
ORGANISM(S): Homo Sapiens 
2022-09-07 | PXD036554 |
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