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UnknownIntegrated mapping, chromosomal sequencing and sequence analysis of Cryptosporidium parvum.
The apicomplexan Cryptosporidium parvum is one of the most prevalent protozoan parasites of humans. We report the physical mapping of the genome of the Iowa isolate, sequencing and analysis of chromosome 6, and approximately 0.9 Mbp of sequence sampled from the remainder of the genome. To construct ...
S-EPMC403770 | biostudies-literature
UnknownProgressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.

Rationale

Amplification of distal 3q is the most common genomic aberration in squamous lung cancer (SQC). SQC develops in a multistage progression from normal bronchial epithelium through dysplasia to invasive disease. Identifying the key driver events in the early pathogenesis of SQC will f...
S-EPMC2902760 | biostudies-literature
UnknownThe genome of the social amoeba Dictyostelium discoideum.
The social amoebae are exceptional in their ability to alternate between unicellular and multicellular forms. Here we describe the genome of the best-studied member of this group, Dictyostelium discoideum. The gene-dense chromosomes of this organism encode approximately 12,500 predicted proteins, a ...
S-EPMC1352341 | biostudies-literature
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