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TranscriptomicsTofu decreases serum lipid levels and modulates hepatic gene expression involved in lipid metabolism in rats
The effects of freeze-dried tofu, a traditional Japanese soy food, were compared with those of major active soy components, protein and isoflavone, by observing physiological differences and global transcriptomes in the liver of male rats. The GeneChip data was normalized and summarized by using Sup...
ORGANISM(S): Rattus norvegicus 
2011-08-26 | E-GEOD-23748 | biostudies-arrayexpress
TranscriptomicsLife-long caloric restriction-associated remodeling of rat white adipose tissue
This study explored the role of the growth hormone (GH) / insulin-like growth factor 1 (IGF-1) axis on the life-long caloric restriction (CR)-associated remodeling of white adipose tissue (WAT). Adipocyte size and gene expression profiles, using high-density oligonucleotide microarrays, were analyze...
ORGANISM(S): Rattus norvegicus 
2012-09-27 | E-GEOD-30668 | biostudies-arrayexpress
TranscriptomicsCognitive dysfunction and amyloid beta accumulation are ameliorated by the ingestion of green soybean extract in aged mice
The prevention or delay of brain senescence would enhance the quality of life for older persons. We investigated the effects of soybean extracts in senescence-accelerated (SAMP10) mice. This mouse is a model of brain senescence with a short life span, cerebral atrophy and cognitive dysfunction. Mice...
ORGANISM(S): Mus musculus 
2014-06-26 | E-GEOD-58811 | biostudies-arrayexpress
TranscriptomicsA comparative analysis of genistein and daidzein in affecting lipid metabolism in rat liver
Effects of soy isoflavones, genistein and daidzein, on the hepatic gene expression profile and indices for lipid metabolism were compared in rats. The GeneChip data was normalized and summarized by using SuperNORM data service (Skylight Biotech Inc.). Significance of expressional change among groups...
ORGANISM(S): Rattus norvegicus 
2012-10-10 | E-GEOD-41420 | biostudies-arrayexpress
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