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TranscriptomicsIdentification of Sox9-Regulated Pathways During Early Pancreas Organogenesis
Sox9 target genes were identified by comparing gene expression in Sox9-ablated versus wild-type pancreata using microarray analysis. Sox9 was conditionally ablated in the developing pancreas via recombination of a Sox9-flox allele (Kist et al., 2002) using the Pdx1-Cre transgene (Gu et al., 2002). T...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-28669 | biostudies-arrayexpress
UnknownA hydrophobic low-complexity region regulates aggregation of the yeast pyruvate kinase Cdc19 into amyloid-like aggregates in vitro.
Not available
S-EPMC6065187 | biostudies-literature
TranscriptomicsIdentification of Sox9-Regulated Pathways During the Secondary Transition Stage of Pancreas Development
Sox9 target genes were identified during the secondary transition stage of pancreas development by comparing gene expression in Sox9-ablated versus wild-type pancreata using microarray analysis. Sox9 was conditionally ablated during the secondary transition in the developing pancreas via recombinati...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-28670 | biostudies-arrayexpress
TranscriptomicsIdentification of Sox9-Regulated Pathways During Pancreas Development
This SuperSeries is composed of the following subset Series: GSE28669: Identification of Sox9-Regulated Pathways During Early Pancreas Organogenesis GSE28670: Identification of Sox9-Regulated Pathways During the Secondary Transition Stage of Pancreas Development Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-28671 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-13:02:22:609-63 - samples
This dataset contains paired fastq files for LMS tumor samples
EGAD00001003828 | EGA
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-13:14:23:391-67 - samples
The data set contains paired end fastq files for whole exome sequencing data for Leiomyosarcoma tumor and control samples
EGAD00001003829 | EGA
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-12:36:36:554-60 - samples
The data set contains bam files aligned using bwa-0.7.8 mem -t 8 -R.
EGAD00001003827 | EGA
GenomicsIntegrative genomic and transcriptomic analysis of adult leiomyosarcoma (HIPO-028, HIPO-018, HIPO-021)
Leiomyosarcoma (LMS) is an aggressive mesenchmyal malignancy with few therapeutic options. The mechanisms underlying LMS development, including clinically actionable genetic vulnerabilities, are largely unknown. We performed genomic and transcriptomic profiling of a large cohort of LMS tumors and id...
EGAS00001002437 | EGA
GenomicsDKFZ-HIPO Data Access Committee of Heidelberg Center for Personalized Oncology
Data Access Committee EGAC00001000452
EGAC00001000452 | EGA
GenomicsSalt augments macrophage-driven host defense in the skin
Immune cells regulate a hypertonic microenvironment in the skin; however, possible functions of increased skin Na+ concentrations are unknown. We found that Na+ accumulated at the site of bacterial skin infections in humans and in mice. We used the protozoan parasite Leishmania (L.) major as a model...
ORGANISM(S): Mus musculus 
2015-02-26 | E-MTAB-3343 | biostudies-arrayexpress
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