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UnknownBrain aging rejuvenation factors in adults with genetic and sporadic neurodegenerative disease.
The largest risk factor for dementia is age. Heterochronic blood exchange studies have uncovered age-related blood factors that demonstrate 'pro-aging' or 'pro-youthful' effects on the mouse brain. The clinical relevance and combined effects of these factors for humans is unclear. We examined five p...
S-EPMC11734525 | biostudies-literature
UnknownGWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Cerebrospinal fluid (CSF) tau, tau phosphorylated at threonine 181 (ptau), and Aβ₄₂ are established biomarkers for Alzheimer's disease (AD) and have been used as quantitative traits for genetic analyses. We performed the largest genome-wide association study for cerebrospinal fluid (CSF) tau/ptau le...
S-EPMC3664945 | biostudies-literature
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