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GenomicsHigh-throughput semi-quantitative analysis of insertional mutations in heterogeneous tumors
Exploiting the full potential of insertional mutagenesis screens with retroviruses and transposons requires methods for distinguishing clonal from subclonal insertion events within heterogeneous tumor cell populations. Current protocols, based on ligation mediated PCR, depend on endonuclease based f...
ORGANISM(S): Mus musculus 
2011-08-11 | E-GEOD-22657 | biostudies-arrayexpress
UnknownAnalysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.
Not available
S-EPMC3653918 | biostudies-literature
UnknownOvarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.
Not available
S-EPMC4167545 | biostudies-literature
UnknownNext generation sequencing of triple negative breast cancer to find predictors for chemotherapy response.
Not available
S-EPMC4592753 | biostudies-literature
TranscriptomicsOvarian Cancer Cell line Panel (OCCP): gene expression data.
Epithelial ovarian cancer is a very heterogeneous disease and remains the most lethal gynaecological malignancy in the Western world. Rational therapeutic approaches need to account for interpatient and intratumoral heterogeneity in treatment design. Detailed characterization of in vitro models repr...
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-53418 | biostudies-arrayexpress
UnknownChromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.
Not available
S-EPMC3333773 | biostudies-literature
UnknownThe molecular genetic make-up of male breast cancer.
Not available
S-EPMC6938562 | biostudies-literature
UnknownClinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study.
Not available
S-EPMC9979766 | biostudies-literature
UnknownThe predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.
Not available
S-EPMC8460445 | biostudies-literature
UnknownCopy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers.
Not available
S-EPMC9537519 | biostudies-literature
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