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TranscriptomicsThe effects of leptin deficiency on cold-induced energy expenditure
At 24 °C Lep-/- mice are hyperphagic compared to the Lep+/+ mice. Reducing the ambient temperature from 24 to 6 °C (3 °C per day) was accompanied by a graded parallel increase in food intake in both control and Lep-/- mice. The rate of increase in food intake per degree Celsius reduction in ambient ...
ORGANISM(S): Mus musculus 
2015-06-15 | E-GEOD-59517 | biostudies-arrayexpress
TranscriptomicsPost-natal development of brown adipocytes in white fat: Phases independent and dependent of the ambient temperature
Decreased ambient temperature, from birth to weaning, significantly reduced fat mass (FM) and adiposity in developing mice. Changes in FM content in 10 day-old mice raised at 17°C were not accompanied by precocious induction of brown adipocytes in inguinal white adipose tissue (WAT). Brown phenotype...
ORGANISM(S): Mus musculus 
2015-05-03 | E-GEOD-62350 | biostudies-arrayexpress
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