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Poly(A) binding proteins (PABPs) regulate mRNA fate by controlling mRNA stability and translation through interactions with both the poly(A) tail and eIF4F complex. Here we identified a protein interaction cohort for both T. brucei PABPs by cryo-mill/affinity purification-mass spectrometry.
ORGANISM(S): Trypanosoma brucei 
2018-07-16 | PXD008839 | Pride
Spores of the bacterium Bacillus cereus can cause disease in humans due to contamination of raw materials for food manufacturing. These dormant, resistant spores can survive for years in the environment, but can germinate and grow when their surroundings become suitable, and spore germination protei...
ORGANISM(S): Bacillus Cereus (ncbitaxon:1396) 
2022-01-24 | MSV000088726 | MassIVE
The ability of oncogenes to provoke cancer is harnessed by regulators that control cell proliferation or induce apoptosis, and bypass of these checkpoints is a hallmark of malignancies. Myc oncoproteins are overexpressed in ~70% of all cancers and induce numerous transcription targets that regulate ...
ORGANISM(S): Mus musculus 
There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of exosomes in 426 human samples from tissue explants (TE), plasma and other bodily fluids. Among traditional exosome markers, CD9, HSPA8, ALIX, HSP90AB1 represent ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-08-17 | PXD018301 | Pride
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