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UnknownComparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA.
Not available
S-EPMC6075789 | biostudies-literature
UnknownNatural variation in the ZmPIMT1 promoter enhances seed aging tolerance by regulating PABP2 repair in maize.
Not available
S-EPMC12510314 | biostudies-literature
ProteomicsProximity labelling and cryomill affinity purification compared for Trypanosoma brucei proteins with unconfined, semi-confined and confined localisation
Identification of protein-protein interactions is a major contributor for understanding protein function and elucidating molecular and cellular mechanisms. Two strategies are currently popular for identification of protein interaction partners directly from the cellular environment. Affinity purific...
ORGANISM(S): Trypanosoma brucei 
2022-11-30 | PXD031245 | Pride
Cryomilling Affinity purification Proteome Bioid Interactome 
ProteomicsInteractome of the two T. brucei Poly(A) binding protein paralogs PABP1and PABP2
Poly(A) binding proteins (PABPs) regulate mRNA fate by controlling mRNA stability and translation through interactions with both the poly(A) tail and eIF4F complex. Here we identified a protein interaction cohort for both T. brucei PABPs by cryo-mill/affinity purification-mass spectrometry.
ORGANISM(S): Trypanosoma brucei 
2018-07-16 | PXD008839 | Pride
Pabp1 Pabp2 Poly(a) binding Trypanosoma brucei Mrna stability Interactome 
TranscriptomicsNext generation sequencing of transcripts associated to five selected RNA-binding proteins in Leishmania infantum
We report the sequencing of mRNAs associated with three Leishmania infantum Poly (A) binding proteins (PABP1, PABP2 and PABP3) and two of their partner RNA binding proteins (RBP23 and DRBD2). PABP1 and RBP23 preferentially associate with mRNAs that encode ribosomal proteins, absent from DRBD2-associ...
ORGANISM(S): Leishmania infantum 
2020-11-11 | GSE161150 | GEO
TranscriptomicsGenome-wide maps of polyadenylation sites in OPMD-model and control mice
We applied deep-sequencing based technique, 3'-Seq, to obtain comprehansive maps of poly-A sites in OPMD-model mice expressing trePABPN1(A17) mutant and control mice Examination of poly-A sites in control and OPMD-model mice (in two ages: 20 weeks and 12 months)
ORGANISM(S): Mus musculus 
2012-04-15 | E-GEOD-32302 | biostudies-arrayexpress
UnknownDifferential localization of the two T. brucei poly(A) binding proteins to the nucleus and RNP granules suggests binding to distinct mRNA pools.
Not available
S-EPMC3559699 | biostudies-literature
UnknownPoly (A) binding protein 2 is critical for stem cell differentiation during regeneration in the planarian Schmidtea mediterranea.
Not available
S-EPMC11456742 | biostudies-literature
ProteomicsMass spectrometry analysis of two RNA-binding proteins, RBP23 and DRBD2, partners of different Poly(A) Binding proteins (PABP) homologues in Leishmania infantum
RNA binding proteins (RBP) have multiple roles associated with mRNA stability and translation. In the Leishmania genus, three Poly(A) Binding Proteins (PABP) were encoded with yet undefined functional distinctions but previous studies of mass-spectrometry identified RBPs differentially associated wi...
ORGANISM(S): Leishmania infantum JPCM5 
2021-11-02 | PXD022480 | Pride
Leishmania Rbp23 Drbd2 
TranscriptomicsPABPN1 role in regulation of alternative cleavage and polyadenylation
This SuperSeries is composed of the following subset Series: GSE27452: Genome-wide maps of polyadenylation sites in control and PABPN1kd cells GSE32302: Genome-wide maps of polyadenylation sites in OPMD-model and control mice Refer to individual Series
ORGANISM(S): Mus musculus 
2012-04-14 | E-GEOD-32303 | biostudies-arrayexpress
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