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ProteomicsMass spectrometry analysis of two RNA-binding proteins, RBP23 and DRBD2, partners of different Poly(A) Binding proteins (PABP) homologues in Leishmania infantum
RNA binding proteins (RBP) have multiple roles associated with mRNA stability and translation. In the Leishmania genus, three Poly(A) Binding Proteins (PABP) were encoded with yet undefined functional distinctions but previous studies of mass-spectrometry identified RBPs differentially associated wi...
ORGANISM(S): Leishmania infantum JPCM5 
2021-11-02 | PXD022480 | Pride
Leishmania Rbp23 Drbd2 
UnknownUnveiling the partners of the DRBD2-mRNP complex, an RBP in Trypanosoma cruzi and ortholog to the yeast SR-protein Gbp2.
Not available
S-EPMC6560856 | biostudies-literature
TranscriptomicsNext generation sequencing of transcripts associated to five selected RNA-binding proteins in Leishmania infantum
We report the sequencing of mRNAs associated with three Leishmania infantum Poly (A) binding proteins (PABP1, PABP2 and PABP3) and two of their partner RNA binding proteins (RBP23 and DRBD2). PABP1 and RBP23 preferentially associate with mRNAs that encode ribosomal proteins, absent from DRBD2-associ...
ORGANISM(S): Leishmania infantum 
2020-11-11 | GSE161150 | GEO
UnknownIdentification of novel proteins and mRNAs differentially bound to the Leishmania Poly(A) Binding Proteins reveals a direct association between PABP1, the RNA-binding protein RBP23 and mRNAs encoding ribosomal proteins.
Not available
S-EPMC8575317 | biostudies-literature
GenomicsNext generation sequencing of transcripts associated to five selected RNA-binding proteins in Leishmania infantum
Next generation sequencing of transcripts associated to five selected RNA-binding proteins in Leishmania infantum
PRJNA675759 | ENA
ProteomicsAffinity Purification of ISWI chromatin remodeler in Trypanosoma cruzi
Chromatin remodeling is a general mechanism involved in DNA-dependent processes, including gene expression regulation. ISWI ATPase is the catalytic subunit in diverse chromatin remodeling complexes that changing histone–DNA interactions and therefore play a pivotal role in different nuclear processe...
ORGANISM(S): Trypanosoma cruzi Dm28c 
2020-05-22 | PXD017869 | Pride
Affinity purification Iswi Trypanosoma cruzi Lc-ms/ms 
UnknownCharacterising ISWI chromatin remodeler in Trypanosoma cruzi.
Not available
S-EPMC7233268 | biostudies-literature
ProteomicsMass spectrometry analysis of four translation initiation proteins, EIF4E3, EIF4E4, EIF4G3 and EIF4G4 in Trypanosoma brucei
Gene expression in pathogenic protozoans of the family Trypanosomatidae has several novel features, for example in protein synthesis there are multiple eIF4F-like complexes. The eukaryotic eIF4F complex, formed by the eIF4E, eIF4G and eIF4A subunits, is responsible for the canonical selection of mRN...
ORGANISM(S): Trypanosoma brucei 
2023-03-10 | PXD033857 | Pride
Trypanosoma brucei  eif4e  eif4g 
UnknownDistinct mRNA and protein interactomes highlight functional differentiation of major eIF4F-like complexes from Trypanosoma brucei.
Not available
S-EPMC9585242 | biostudies-literature
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