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This study explores the mechanisms of cardiotoxicity of the three widespread model polycyclic aromatic hydrocarbons retene, pyrene and phenanthrene in the rainbow trout (Oncorhyncus mykiss) early life stages. Newly hatched larvae were exposed to each individual compound at sublethal doses: DMSO (con...
ORGANISM(S): Oncorhynchus mykiss 
In this project, effects of chronic temperature changes on the transcriptome of the rainbow trout heart (Oncorhynchus mykiss) were examined. Ectothermic animals of north-temperate latitudes experience large seasonal changes in temperature which strongly affect the rate of body functions. To compensa...
ORGANISM(S): Oncorhynchus mykiss 
Gene expression profiling revealed rapid activation of immunity, both local and systemic, which however did not provide protection of fish against the parasite. Major changes of transcriptome responses wwere observed between days 5 and 10 Atlantic salmon was challenged with L. salmonis at the copepo...
ORGANISM(S): Salmo salar 
The study searched for the correlates of vaccine protection against furunculosis. After pathogen challenge of vaccinated (V) and unvaccinated (N) fish, hepatic gene expression was compared in salmon with high resistance (HR, individual samples) and low resistance (LR, pooled samples) Two-condition e...
ORGANISM(S): Salmo salar 
M74 developmental disorder is characterized with high mortality in salmon fry. Samples are categorized by the onset and stage of disease; analyses were conduced in a dye swap design
ORGANISM(S): Salmo salar 
Changes of gene expression in primary cell cultures of salmon adipose-derived stromal-vascular fraction were studied at six time-points that covered the key differentiation events: confluence, clonal expansion, determination and establishment of the mature adipocyte phenotype. Time-course experiment...
ORGANISM(S): Salmo salar 
The study evaluated effects of dietary cholesterol (1.5%) in Atlantic salmon fed a plant based diet for 77 days. Cholesterol supplementation did not affect growth or organ weights of Atlantic salmon, but promoted induction of cholesterol and plant sterol efflux in the intestine, whereas sterol uptak...
ORGANISM(S): Salmo salar 
The aquatic orthomyxovirus infectious salmon anemia virus (ISAV) is an important pathogen for salmonid aquaculture, however little is known about protective and pathological host responses to infection. We have investigated intracellular responses during cytopathic ISAV infection in the macrophage-l...
ORGANISM(S): Salmo salar 
The response of the trout, O.mykiss, head kidney to bacterial lipopolysaccharide (LPS) or active and attenuated infectious hematopoietic necrosis virus (IHNV and attINHV respectively) intraperoniteal challenge, 24 and 72 hours post-injection, was investigated using a salmonid-specific cDNA microarra...
ORGANISM(S): Oncorhynchus mykiss 
Long-term exposure of Atlantic salmon to 19M-BM-0C resulted in cardiac gene and protein expression changes indicating that the unfolded protein response, vascularization, remodeling of connective tissue and altered innate immune responses were part of the cardiac acclimation or response to elevated ...
ORGANISM(S): Salmo salar 
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