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TranscriptomicsIdentification of microarray probe signals constantly present in multiple sample types
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-10 | E-GEOD-39528 | biostudies-arrayexpress
TranscriptomicsNuclear scaffold and matrix attachment of Aortic Adventitial Fibroblast (AoAF) chromatin
The nuclear scaffold/matrix provides an anchor for higher order genome structure that has both structural and functional implications. Different extraction protocols, i.e., utilizing either 25 mM LIS or 2 M NaCl, isolate somewhat different protein constituents of either the nuclear scaffold or nucl...
ORGANISM(S): Homo sapiens 
2009-03-10 | E-GEOD-13792 | biostudies-arrayexpress
TranscriptomicsNuclear scaffold and matrix attachment of HeLa chromatin
The nuclear scaffold/matrix provides an anchor for higher order genome structure that has both structural and functional implications. Different extraction protocols, i.e., utilizing either 25 mM LIS or 2 M NaCl, isolate somewhat different protein constituents of either the nuclear scaffold or nucl...
ORGANISM(S): Homo sapiens 
2010-05-22 | E-GEOD-13774 | biostudies-arrayexpress
TranscriptomicsCharacterization of the small RNA population in Human spermatozoa
Small noncoding RNAs (sncRNA) are becoming recognized for their participation in a diverse range of cellular functions. In this study, their global characterization in human spermatozoa from donors with proven fertility was undertaken. Reads were analyzed in two classes, those mapping to unique loca...
ORGANISM(S): Homo sapiens 
2011-10-15 | E-GEOD-21191 | biostudies-arrayexpress
TranscriptomicsIdentification of microarray probe signals constantly present in multiple sample types (part 1)
The correlation of the RNA profiles obtained by microarray analysis was compared with that obtained from RNA-Seq by using reduced complexity sperm datasets. This resolved as a series of discordant probes. The extent of discordancy among other datasets was then determined. A correlative study between...
ORGANISM(S): Homo sapiens 
2013-06-10 | E-GEOD-39526 | biostudies-arrayexpress
TranscriptomicsrRNA cleavage ensures translational cessation in the mature sperm
We report how unique RNA seq profiles of ribosomal RNA (18S, 28S) present in sperm indicate specific cleavage sites. Additionally, these sequencing results reveal how overall character of RNA (GC content) can significantly affect overall distribution of mapped reads. Examination of rRNA population ...
ORGANISM(S): Homo sapiens 
2013-03-11 | E-GEOD-29160 | biostudies-arrayexpress
TranscriptomicsIdentification of microarray probe signals constantly present in multiple sample types (part 2)
The correlation of the RNA profiles obtained by microarray analysis was compared with that obtained from RNA-Seq by using reduced complexity sperm datasets. This resolved as a series of discordant probes. The extent of discordancy among other datasets was then determined. A correlative study between...
ORGANISM(S): Homo sapiens 
2013-06-10 | E-GEOD-39527 | biostudies-arrayexpress
TranscriptomicsNuclear Matrix Association in Proliferative and Invasive Cytotrophoblasts
Abnormal trophoblast invasion is associated with the most common and most severe complications of human pregnancy. The biology of invasion, as well as the etiology of abnormal invasion remains poorly understood. The aim of this study was to characterize the transcriptome of the HTR-8/SVneo human c...
ORGANISM(S): Homo sapiens 
2010-06-22 | E-GEOD-17501 | biostudies-arrayexpress
TranscriptomicsH4K12 acetylation in Human Spermatozoa
H4K12 acetylation mapped by chromatin Chromatin immunoprecipitation (ChIP) in human sperm. ChIP mapping of chromatin modification. Three biological replicates hybridized to each of two chips.
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-13101 | biostudies-arrayexpress
TranscriptomicsThe Partitioning of RNAs in sperm
A diverse pool of RNAs remain encapsulated within the transcriptionally and translationally silent spermatozoon. These transcripts persist within the male gamete despite the dramatic reduction in cellular volume achieved through expulsion of the cytoplasm and quite possibly the nucleoplasm. The prec...
ORGANISM(S): Mus musculus 
2015-07-08 | E-GEOD-62874 | biostudies-arrayexpress
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