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TranscriptomicsDeep Sequencing of the Porcine Endometrial Transcriptome on Day 14 of Pregnancy
In pigs, conceptus attachment to the uterine surface epithelium starts around day 14 of pregnancy preceded by a pronounced vascularization at the implantation zones, initiating the epitheliochorial placentation. To characterize the complex transcriptome changes in the endometrium in the course of in...
ORGANISM(S): Sus scrofa 
2013-03-07 | E-GEOD-43667 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of the porcine endometrial transcriptome on day 12 of pregnancy
The porcine conceptus undergoes rapid differentiation and expansion of its trophoblastic membranes between Days 11 and 12 of gestation. Concomitant with trophoblast elongation, production of conceptus estrogen, the porcine embryonic pregnancy recognition signal increases. Conceptus attachment to the...
ORGANISM(S): Sus scrofa 
2013-10-31 | E-GEOD-48862 | biostudies-arrayexpress
TranscriptomicsFine mapping of genome activation in bovine embryos by RNA sequencing
During maternal-to-embryonic transition control of embryonic development gradually switches from maternal RNAs and proteins stored in the oocyte to gene products generated after embryonic genome activation (EGA). Detailed insight into the onset of embryonic transcription is obscured by the presence ...
ORGANISM(S): Bos taurus 
2014-02-09 | E-GEOD-52415 | biostudies-arrayexpress
TranscriptomicsRNA-seq in Raji cells with inducible BZLF1 prior to and after induction of EBV's lytic cycle by doxycycline
(i) RNA transcripts of Raji iBZLF1 cells (https://www.biorxiv.org/content/10.1101/573659v1) were compared between non-induced cells and cells induced with doxycycline (100 ng/ ml) for 6 h. Human (Hg19) as well as viral (EBV, Raji KF717093.1) transcripts were analyzed. Artificial ERCC Spike-ins (Ther...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-7820 | biostudies-arrayexpress
MetabolomicsMitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling flux of the TCA cycle

To elucidate the function of oxidative phosphorylation (OxPhos) during B-cell differentiation we employ CD23Cre-driven expression of the dominant-negative K320E mutant of the mitochondrial helicase Twinkle (DNT). DNT-expression depletes mitochondrial DNA during B cell maturation, reduces the abun...

2026-08-21 | MTBLS4647 | MetaboLights
TranscriptomicsRNA-seq data from DG75 cells with inducible BZLF1 prior to and after induction of EBV's lytic cycle by doxycycline.
(i) Transcripts of DG75 iBZLF1 cells were analyzed comparing non-induced cells and cells induced with doxycycline (100 ng/ ml) for 6 h. Doxycycline induces the expression of the full length viral transcription factor BZLF1. (ii) For control purposes, the transcripts of DG75 cells equipped with a dox...
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-8426 | biostudies-arrayexpress
TranscriptomicsChIP-seq against BZLF1 in DG75 cells (EBV-negative, human Burkitt lymphoma cell line)
The parental DG75 cell line is EBV negative and cannot express the viral BZLF1 protein, thus, this set of experiments served as a negative control. After ChIP, peaks were identified in both the human and viral (EBV (Human Herpesvirus 4) genome KF717093.1) genome. Only few peaks were identified. Expe...
ORGANISM(S): Homo sapiens 
2019-04-05 | E-MTAB-7821 | biostudies-arrayexpress
UnknownSOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.
Not available
S-EPMC133908 | biostudies-literature
TranscriptomicsCapture-C identification of chromatin interactions of 53 selected cellular loci prior to and post induction of EBV's lytic cycle in Raji cells
Identification of specific chromatin interactions of 53 selected genes with the Capture-C technique in Raji iBZLF1 cells prior to and 6 or 15 h after induction of EBV’s lytic cycle. The experiments were performed as triplicates.
ORGANISM(S): Homo sapiens 
2019-04-05 | E-MTAB-7825 | biostudies-arrayexpress
TranscriptomicsIdentification of chromatin interactions of 49 selected cellular loci prior to and post induction of BZFL1 in DG75 cells using the Capture-C technology.
Identification of specific chromatin interactions of 49 selected genes with the Capture-C technique in DG75 iBZLF1 cells prior to and 15 h after expression of EBV's protein BZLF1. The experiments were performed as triplicates.
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-8427 | biostudies-arrayexpress
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