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TranscriptomicsHuman nephrosclerosis triggers a hypoxia-related glomerulopathy.
Expression data from microdissected glomeruli to examine the role of hypoxia in glomerulosclerosis of human Nephrosclerosis (NSC). Human Kidney biopsies of patients with NSC (n=14) and TN (n=4) were selected for RNA extraction and hybridization on Affymetrix microarrays. Gene expression data was the...
ORGANISM(S): Homo sapiens 
2010-03-30 | E-GEOD-20602 | biostudies-arrayexpress
TranscriptomicsExpression data from human healthy CD133+ bone marrow EPCs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-α plays a crucial role in premature vascular damage in SLE. IFN-α alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-26951 | biostudies-arrayexpress
TranscriptomicsExpression data from human healthy and lupus EPCs/CACs, and healthy CD133+ bone marrow EPCs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-α plays a crucial role in premature vascular damage in SLE. IFN-α alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-23203 | biostudies-arrayexpress
TranscriptomicsExpression data from human healthy EPCs/CACs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-? plays a crucial role in premature vascular damage in SLE. IFN-? alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-26949 | biostudies-arrayexpress
TranscriptomicsExpression data from human lupus EPCs/CACs
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to premature atherosclerosis independent of traditional risk factors. We previously proposed that interferon-α plays a crucial role in premature vascular damage in SLE. IFN-α alters the balance between endothelial cel...
ORGANISM(S): Homo sapiens 
2011-04-13 | E-GEOD-26950 | biostudies-arrayexpress
TranscriptomicsSystematic analysis of a human renal transcript dataset
Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key relevance for glomerular function. Quite a few of these genes show a specific or preferential mRNA expression in the renal glomerulus. To identify additional candidate genes ...
ORGANISM(S): Homo sapiens 
2010-07-19 | E-GEOD-21785 | biostudies-arrayexpress
TranscriptomicsThe molecular phenotype of endocapillary proliferation in IgA nephropathy and potential modulation by bioactive small molecules
Endocapillary proliferation is associated with higher risk of progressive disease in IgAN. To better understand molecular pathways involved in the development of endocapillary proliferation and to identify novel specific therapeutic targets, we evaluated the glomerular transcriptome of microdissecte...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-50469 | biostudies-arrayexpress
TranscriptomicsGlomerular Transcriptome from European Renal cDNA Bank subjects and living donors
Glomerular Transcriptome from European Renal cDNA Bank subjects and living donors. Samples included in this analysis have been previously analyzed using older CDF definitions and are included under previous GEO submissions - GSE47183 (chronic kidney disease samples), and GSE32591 (IgA nephropathy sa...
ORGANISM(S): Homo sapiens 
2018-01-24 | E-GEOD-104948 | biostudies-arrayexpress
TranscriptomicsTubulointerstitial transcriptome from ERCB subjects with chronic kidney disease and living donor biopsies.
Tubulointerstitial transcriptome from ERCB subjects with chronic kidney disease and living donor biopsies. Samples included in this analysis have been previously analyzed using older CDF definitions and are included under previous GEO submissions - GSE47184 (chronic kidney disease samples), and GSE3...
ORGANISM(S): Homo sapiens 
2018-01-24 | E-GEOD-104954 | biostudies-arrayexpress
TranscriptomicsGlomerular transcriptome from subjects in the NEPTUNE cohort
Glomerular Transcriptome from subjects in the NEPTUNE cohort. A number of samples profiled in this analysis were also profiled in Series GSE68127, and Series GSE108113. RNA from the glomerular compartment of was extracted and processed for hybridization on Affymetrix microarrays. Contributor: NEPTU...
ORGANISM(S): Homo sapiens 
2018-05-17 | E-GEOD-104066 | biostudies-arrayexpress
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