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OtherComprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells.
Data from ProteomeXchange, PXD ID: PXD001416. File: PBMC_1_con_cyt1-4.mgf. Published as part of J Proteome Res. 2014 Oct 27 . From the Abstract: {{i}} Monitoring proteins involved in regulatory effects may help to improve our understanding of inflammation. We have analyzed proteome alterations indu...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320004830 | GPMDB
Resource Reanalysis 
OtherProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.
Data from ProteomeXchange, PXD ID: PXD001323. Experiment: hmf_cyt_TGFb_1, file: hmf_cyt_TGFb_1_2.mzml. Published as part of J Proteome Res. 2014 Sep 19. . From the Abstract: {{i}} Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attribu...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320003614 | GPMDB
Resource Reanalysis 
OtherProteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts.
Data from ProteomeXchange, PXD ID: PXD001324. Experiment: P1, file: P1_Cyt_Near_4.mzml. Published as part of J Proteome Res. 2014 Sep 19. . From the Abstract: {{i}} Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-a...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM11210030024 | GPMDB
Resource Reanalysis 
ProteomicsResponse Profiling Using Shotgun Proteomics Enables Establishing Global Metallodrug Mechanisms of Action - cytoplasmic proteins of KP1537-treated SW480 epithelial cells
Response profiling using shotgun proteomics for establishing global metallodrug mechanisms of action in two colon carcinoma cell lines, HCT116 and SW480, was applied and evaluated with the clinically approved arsenic trioxide. Surprisingly, the complete established mechanism of action of arsenic tr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080730 | MassIVE
ProteomicsResponse Profiling Using Shotgun Proteomics Enables Establishing Global Metallodrug Mechanisms of Action - cytoplasmic proteins of untreated HCT 116 epithelial cells
Response profiling using shotgun proteomics for establishing global metallodrug mechanisms of action in two colon carcinoma cell lines, HCT116 and SW480, was applied and evaluated with the clinically approved arsenic trioxide. Surprisingly, the complete established mechanism of action of arsenic tr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080737 | MassIVE
ProteomicsResponse Profiling Using Shotgun Proteomics Enables Establishing Global Metallodrug Mechanisms of Action - cytoplasmic proteins of KP772-treated SW480 epithelial cells
Response profiling using shotgun proteomics for establishing global metallodrug mechanisms of action in two colon carcinoma cell lines, HCT116 and SW480, was applied and evaluated with the clinically approved arsenic trioxide. Surprisingly, the complete established mechanism of action of arsenic tr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080736 | MassIVE
ProteomicsResponse Profiling Using Shotgun Proteomics Enables Establishing Global Metallodrug Mechanisms of Action - cytoplasmic proteins of KP1339-treated SW480 epithelial cells
Response profiling using shotgun proteomics for establishing global metallodrug mechanisms of action in two colon carcinoma cell lines, HCT116 and SW480, was applied and evaluated with the clinically approved arsenic trioxide. Surprisingly, the complete established mechanism of action of arsenic tr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080734 | MassIVE
ProteomicsComprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - nuclear proteins of untreated cells
Inflammation is a physiological process involved in many diseases. Monitoring proteins involved in regulatory effects may help to improve our understanding of inflammation. We have analyzed proteome alterations induced in peripheral blood mononuclear cells (PBMCs) upon inflammatory activation in gre...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079943 | MassIVE
ProteomicsQuantification of cytokines secreted by primary human cells using MRM: evaluation of analytical parameters â?? shotgun secretome data of inflammatory stimulated HUVECs
The determination of secreted proteins may provide highly valuable information about cell functions. While the typical methods for the determination of biologically relevant but low-abundant molecular species still relies on the use of specific antibodies, mass spectrometry-based methods are now gai...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079982 | MassIVE
ProteomicsComprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells - Cytoplasmic Proteins of Untreated Cells
Inflammation is a physiological process involved in many diseases. Monitoring proteins involved in regulatory effects may help to improve our understanding of inflammation. We have analyzed proteome alterations induced in peripheral blood mononuclear cells (PBMCs) upon inflammatory activation in gre...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079971 | MassIVE
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