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TranscriptomicsmiRNA analysis of HBMVECs exposed or unexposed to U87 glioma cells
A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here we demonstrate that a small regulatory microRNA, miR-296 has a major role in this process. Glioma cells and angiogenic growth factors elevate the level of miR-296 in primary human brain microvascular...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13091 | biostudies-arrayexpress
TranscriptomicsGlioblastoma microvesicles transport RNA and proteins
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells. By incorporating an mRNA for a reporter protein into these microvesicles, we demonstrate th...
ORGANISM(S): Homo sapiens 
2008-11-15 | E-GEOD-13470 | biostudies-arrayexpress
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